Amoebic Liver Abscess: An Appraisal

Singh, Rajinder; Adhikari, Devbrata; Patil, Bhushan; Talathi, Nikhil R.; Hanamshetti, Satish R.; Joshi, Rajeev

doi:10.9738/cc9.1

Cited by 8 publications

(7 citation statements)

References 16 publications

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“…Alcohol (63.2%) was the most common co-morbidity associated with ALA followed by diabetes mellitus (11.4%) which was similar to other studies. 11 In contrast, however, to other studies from India and elsewhere, 12,13 only one patient tested positive for HIV as its incidence is very low in our region of central India.…”

Section: Discussioncontrasting

confidence: 78%

Amoebic liver abscess: a report from central India

Chaudhary¹,

Noor²,

Jain³

et al. 2015

Trop Doct

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Amoebic liver abscess is a serious but curable hepatic illness predominantly seen in tropical countries. We describe our experience of clinical presentation, laboratory parameters, radiological findings and treatment strategies. This is a retrospective analysis of 114 patients who were admitted from January 2012 to September 2014 at our centre. The mean age of presentation was 41.7 ± 13.9 years, the majority of patients were male (86.8%) with chronic alcoholism (63.2%). Most of the patients had a solitary right lobe liver abscess. Abdominal pain, fever, tachycardia and hepatomegaly were the most common clinical findings while hypoalbuminaemia, anaemia, leucocytosis and electrolyte imbalance were the most common laboratory abnormalities. A significant number of patients could be managed with antibiotics only (45.6%), percutaneous radiological drainage techniques being an important adjunct in selected cases (percutaneous needle aspiration, 20.2%; percutaneous pigtail catheter drainage, 30.7%). Surgical intervention was required in only a few cases (3.5%). Mortality was 3.5%.

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Section: Discussioncontrasting

confidence: 78%

Amoebic liver abscess: a report from central India

Chaudhary¹,

Noor²,

Jain³

et al. 2015

Trop Doct

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“…Similar results have been reported by Mishra et al and Singh and Srivastava studies. 3 Males (93.3%) were predominantly affected with amoebic liver abscess in the present study, which were similar to other studies like Debakey and Oschner, Raghavan et al, Habibullah et al and Katzenstein et al 4,5,6,7 Out of 45 cases, there were 42 male patients (93.3%) and 3 female patients (6.6%). The male-to-female ratio is 14:1.…”

Section: Discussionsupporting

confidence: 82%

Clinical Presentation and Management of Amoebic Liver Abscess

Naveen¹,

R²,

M³

et al. 2015

jemds

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BACKGROUND AND OBJECTIVESALA has gained importance during recent years as a result of increasing world travel, economic globalization and the growing number of chronically immunosuppressed people. AIDS and the increasing use of organ transplants have led to a new population at risk. In our study we aimed to analyse the clinical presentation and management of Amoebic liver abscess at Sree Rajarajeshwari Medical College and Hospital, Bangalore.

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“…Chloroquine (CQ) and hydroxychloroquine (HCQ) are drugs belonging to the 4-aminoquinoline group and are widely used in the prophylaxis and treatment of malaria ( Price et al, 2014 ; Tanenbaum and Tuffanelli, 1980 ), lupus ( Lee et al, 2011 ), amoebiasis ( Singh et al, 2011 ) and rheumatoid arthritis ( Chung et al, 2007 ; Haque et al, 2008 ), being considered a potential broad-spectrum antiviral agent ( Savarino et al, 2006 ). Its mechanism of action consists of inhibiting the fusion of the virus to the cell membrane by modulating the endosomal pH ( Goodarzi et al, 2020 ).…”

Section: Resultsmentioning

confidence: 99%