Amniotic therapeutic biomaterials in urology: current and future applications

Oottamasathien, Siam; Hotaling, James M.; Craig, James R.; Myers, Jeremy B.; Brant, William O.

doi:10.21037/tau.2017.09.01

Cited by 25 publications

(6 citation statements)

References 47 publications

(46 reference statements)

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“…Native hAM has been applied as a scaffold for TE and regeneration in different medical fields (the reader can find this information in previous sections). Some reviews describe its use as a grafting material, 8 in oral and periodontal surgeries, 23 cartilage damage, 7 lower extremity repair, 121 healing of chronic wounds and ulcers, 122 as a biomaterial in urology, 123,124 in gynecology, 125 as of patch for cardiac surgery, 126 and as a treatment of ocular surface pathologies. 29 In ophthalmology, the transplantation of frozen or fresh hAM is often used for pterygium excision, conjunctival surface reconstruction (e.g., after symblepharon lysis), reepithelialization in corneal ulcer, or for temporary closure of perforated corneas.…”

Section: Applicationsmentioning

confidence: 99%

Human Amniotic Membrane: A review on tissue engineering, application, and storage

et al. 2020

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Human amniotic membrane (hAM) has been employed as scaffolding material in a wide range of tissue engineering applications, especially as a skin dressing and as a graft for corneal treatment, due to the structure of the extracellular matrix and excellent biological properties that enhance both wound healing and tissue regeneration. This review highlights recent work and current knowledge on the application of native hAM, and/or production of hAM-based tissue-engineered products to create scaffolds mimicking the structure of the native membrane to enhance the hAM performance. Moreover, an overview is presented on the available (cryo) preservation techniques for storage of native hAM and tissue-engineered products that are necessary to maintain biological functions such as angiogenesis, anti-inflammation, antifibrotic and antibacterial activity.

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Section: Applicationsmentioning

confidence: 99%

Human Amniotic Membrane: A review on tissue engineering, application, and storage

et al. 2020

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“…Native hAM has been applied as a scaffold for TE and regeneration in different medical fields. Some reviews describe its use as a grafting material [ 69 ] in oral and periodontal surgeries [ 70 ], cartilage damage [ 71 ], lower extremity repair [ 72 ], healing of chronic wounds and ulcers [ 73 ] as a biomaterial in urology [ 74 , 75 ] in gynecology [ 76 ], as of patch for cardiac surgery [ 77 ] and as a treatment of ocular surface pathologies [ 78 ]. The hAM is an outstanding allogeneic graft material.…”

Section: Applicationsmentioning

confidence: 99%

A comprehensive review on methods for promotion of mechanical features and biodegradation rate in amniotic membrane scaffolds

Sarvari

Keyhanvar

Agbolaghi

et al. 2022

J Mater Sci: Mater Med

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Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother’s womb. It has pluripotent cells, immune modulators, collagen, cytokines with anti-fibrotic and anti-inflammatory effect, matrix proteins, and growth factors. In spite of the biological characteristics, some results have been released in preventing the adhesion on traumatized surfaces. Application of the AM as a scaffold is limited due to its low biomechanical resistance and rapid biodegradation. Therefore, for using the AM during surgery, its modification by different methods such as cross-linking of the membrane collagen is necessary, because the cross-linking is an effective way to reduce the rate of biodegradation of the biological materials. In addition, their cross-linking is likely an efficient way to increase the tensile properties of the material, so that they can be easily handled or sutured. In this regard, various methods related to cross-linking of the AM subsuming the composite materials, physical cross-linking, and chemical cross-linking with the glutraldehyde, carbodiimide, genipin, aluminum sulfate, etc. are reviewed along with its advantages and disadvantages in the current work.

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“…Based on the number of surveys conducted or ongoing clinical studies, urology has also played a large part in studies using hAM [84,134,135]. Shakeri et al evaluated hAM as a xenograft for urethroplasty in rabbits [136].…”

Section: Urethralmentioning

confidence: 99%

Applications of Human Amniotic Membrane for Tissue Engineering

et al. 2021

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An important component of tissue engineering (TE) is the supporting matrix upon which cells and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue and provide an excellent environment for cell growth and differentiation. Human amniotic membrane (hAM) is considered as a surgical waste without ethical issue, so it is a highly abundant, cost-effective, and readily available biomaterial. It has biocompatibility, low immunogenicity, adequate mechanical properties (permeability, stability, elasticity, flexibility, resorbability), and good cell adhesion. It exerts anti-inflammatory, antifibrotic, and antimutagenic properties and pain-relieving effects. It is also a source of growth factors, cytokines, and hAM cells with stem cell properties. This important source for scaffolding material has been widely studied and used in various areas of tissue repair: corneal repair, chronic wound treatment, genital reconstruction, tendon repair, microvascular reconstruction, nerve repair, and intraoral reconstruction. Depending on the targeted application, hAM has been used as a simple scaffold or seeded with various types of cells that are able to grow and differentiate. Thus, this natural biomaterial offers a wide range of applications in TE applications. Here, we review hAM properties as a biocompatible and degradable scaffold. Its use strategies (i.e., alone or combined with cells, cell seeding) and its degradation rate are also presented.

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Amniotic therapeutic biomaterials in urology: current and future applications

Cited by 25 publications

References 47 publications

Human Amniotic Membrane: A review on tissue engineering, application, and storage

Human Amniotic Membrane: A review on tissue engineering, application, and storage

A comprehensive review on methods for promotion of mechanical features and biodegradation rate in amniotic membrane scaffolds

Applications of Human Amniotic Membrane for Tissue Engineering

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