Amniotic fluid glucose and cytokines values in the early diagnosis of amniotic infection in patients with preterm labor and intact membranes

González-Bosquet, Eduardo; Cerqueira, Maria J.; Domı́nguez, Carmen; Gasser, I; Bermejo, B.; Cabero, L.

doi:10.3109/14767059909020480

Cited by 15 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, 39.1% of pregnant women with PTL delivered preterm, a percentage that falls within the range of 27-51.3% of preterm deliveries in women with PTL reported in other studies [13,14] . The relatively high percentage of women in the study group with a history of preterm delivery confi rms the fi nding of other authors that it represents a risk factor for preterm delivery in subsequent pregnancies [15,16] .…”

Section: Discussionsupporting

confidence: 87%

Value of Endocervical <i>Ureaplasma </i>Species Colonization as a Marker of Preterm Delivery

Bosquet

Gené²,

Ferrer³

et al. 2006

Gynecol Obstet Invest

View full text Add to dashboard Cite

Aims: To study the predictive value for preterm delivery of colonization of the cervix and vagina by ureaplasmas and other potentially pathogenic microorganisms. Methods: Prospective analysis of a study group of 200 pregnant women with preterm labor and intact membranes, and a control group of 50 pregnant women. The subjects in both groups were between 24 and 34 weeks of gestation. Ureaplasma spp. and Mycoplasma hominis endocervical cultures were performed for both groups. Results: In the study group, 70 of the women delivered preterm, and all women in the control group carried their pregnancies to full term. Cervical cultures for Ureaplasma spp. were positive in 119 women, and were isolated more frequently in the study group (51.5%) than in the control group (32%), and more frequently in subjects in the study group who delivered preterm (65%) than in those who had a full-term delivery (45%), differences that were statistically significant. Conclusion: Detection of Ureaplasma spp. in the endocervix has a statistically significant relationship to preterm labor (p = 0.03) and preterm delivery (p = 0.02) in pregnant women with preterm labor and intact membranes.

show abstract

Section: Discussionsupporting

confidence: 87%

Value of Endocervical <i>Ureaplasma </i>Species Colonization as a Marker of Preterm Delivery

Bosquet

Gené²,

Ferrer³

et al. 2006

Gynecol Obstet Invest

View full text Add to dashboard Cite

show abstract

“…23,24 Amniotic fluid glucose levels were reported to be lower in women with preterm delivery when compared with women who delivered at term. 25,26 In the light of these studies, we aimed to evaluate the role of mid-trimester maternal serum and amniotic fluid biomarkers of inflammation: hs-CRP, IL-6, ALP, LDH, ferritin, ceruloplasmin and glucose which are readily available, inexpensive and rapidly performed in any laboratory, in predicting preterm delivery and IUGR.…”

Section: Introductionmentioning

confidence: 99%

Mid‐trimester maternal serum and amniotic fluid biomarkers for the prediction of preterm delivery and intrauterine growth retardation

Özgü-Erdinç

Cavkaytar

Aktulay

et al. 2014

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…We have reported that i͞u administration of 120, 250, or 500 ng of EGF on d21 of pregnancy delayed the onset of labor in a dose-response fashion (10). The inflammatory cytokines have long been linked to i͞u infection-driven preterm labor (7,8,27,28), and there is accumulating evidence that they are also involved in normal term labor (29,30). In fact, it has been proposed that human parturition represents an inflammatory process.…”

Section: Discussionmentioning

confidence: 99%

“…EGF (murine submaxillar glands, culture grade) was from Calbiochem. [5,6,8,9,11,12,14,15(n)-3 H]PGF 2␣ (160 Ci͞mmol), 17␣-hydroxy[1,2,6,7-3 H]-P (60 Ci͞mmol), and 125 I (0.25 mCi͞ l) were from Amersham Pharmacia. The first antibody against EGF was from IgG Corporation, and the second was provided by Catholic University (Santiago, Chile).…”

Section: Methodsmentioning

confidence: 99%

“…This is consistent with the stimulatory action of EGF on amnion prostaglandins (PGs) biosynthesis, which has led to the suggestion of a role for EGF in parturition (5,6). At the time of delivery in women, some cytokines and growth factors are higher in amniotic fluid (AF) (7,8). Although EGF is sharply increased in AF near delivery, there is no effect of it on the timing of labor (9).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Epidermal growth factor prevents prepartum luteolysis in the rat

Ribeiro¹,

Aisemberg²,

Billi³

et al. 2005

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

We have previously reported that intrauterine (i͞u) administration of epidermal growth factor (EGF 500 ng) on day (d) 21 of pregnancy delayed 19.0 ؎ 0.6 h the onset of labor. Progesterone (P) is secreted by ovarian corpora lutea (CL) throughout gestation in the rat. Prepartum CL regression due to increased uterine cyclooxygenase I and prostaglandin F 2␣ results in P withdrawal followed by labor. The aims of the present work were (i) to study whether EGF delayed-onset of labor was mediated by a mechanism that prevented CL regression; (ii) to determine amniotic fluid (AF) EGF in pregnant rats. Rats on d21 of pregnancy received i͞u EGF (500 ng) and were killed 0, 4, 8, 12, 24, and 48 h later. Control AF from rats on d13 and 18 -22 of pregnancy was obtained. EGF decreased uterine prostaglandin F 2␣ synthesis 8 h after treatment. Twelve hours after EGF injection, P reached its highest serum level and uterine cyclooxygenase I expression was undetectable. CL from rats killed 8 and 12 h after EGF were similar to those from rats on d13 of pregnancy, when serum P is maximum. EGF in AF increased throughout gestation, reached a maximum on d21, and decreased before the onset of labor. We suggest that the effect of EGF on the onset of labor was mediated by an early effect on the uterus that prevented prepartum CL regression.

show abstract

Amniotic fluid glucose and cytokines values in the early diagnosis of amniotic infection in patients with preterm labor and intact membranes

Cited by 15 publications

References 0 publications

Value of Endocervical <i>Ureaplasma </i>Species Colonization as a Marker of Preterm Delivery

Value of Endocervical <i>Ureaplasma </i>Species Colonization as a Marker of Preterm Delivery

Mid‐trimester maternal serum and amniotic fluid biomarkers for the prediction of preterm delivery and intrauterine growth retardation

Epidermal growth factor prevents prepartum luteolysis in the rat

Contact Info

Product

Resources

About