Aims: To study the predictive value for preterm delivery of colonization of the cervix and vagina by ureaplasmas and other potentially pathogenic microorganisms. Methods: Prospective analysis of a study group of 200 pregnant women with preterm labor and intact membranes, and a control group of 50 pregnant women. The subjects in both groups were between 24 and 34 weeks of gestation. Ureaplasma spp. and Mycoplasma hominis endocervical cultures were performed for both groups. Results: In the study group, 70 of the women delivered preterm, and all women in the control group carried their pregnancies to full term. Cervical cultures for Ureaplasma spp. were positive in 119 women, and were isolated more frequently in the study group (51.5%) than in the control group (32%), and more frequently in subjects in the study group who delivered preterm (65%) than in those who had a full-term delivery (45%), differences that were statistically significant. Conclusion: Detection of Ureaplasma spp. in the endocervix has a statistically significant relationship to preterm labor (p = 0.03) and preterm delivery (p = 0.02) in pregnant women with preterm labor and intact membranes.
Aims: To study the value of interleukin (IL)-8, IL-6 and IL-1β in vaginal wash as predictors of preterm delivery. Methods: A prospective analysis of a study group of 200 pregnant women between 24 and 34 weeks of gestation with intact membranes and preterm labor and a control group of 50 pregnant women during the same period of gestation. The controls had uncomplicated pregnancies and subsequently delivered at term. Samples of vaginal secretions were collected from both groups and analyzed for IL-1β, IL-6 and IL-8 concentrations. Results: Of the women in the study group, 70 had preterm deliveries, while all women in the control group had full-term deliveries. Compared with the control group, the study group had significantly higher concentrations (p < 0.021) of IL-1β, IL-6 and IL-8. The women in the study group delivering preterm also had IL-1β, IL-6 and IL-8 concentrations significantly greater (p < 0.001) than those of the same group delivering full term. ROC curves were used to establish cut-off points for the three interleukins to predict preterm delivery. We did not find a cut-off point with an appropriate sensitivity and specificity. Conclusion: The concentrations of interleukins in vaginal wash were significantly higher both in the women with preterm labor and in those delivering preterm. While values differed between controls and those with the preterm labor, no cut-off can be obtained to use the results of IL-1β, IL-6 and IL-8 as a predictor clinically.
Port-site infection is one of the most frequent complications in gynaecological laparoscopy. We present a rare case of port-site infection complicated by an abdominal wall abscess and sepsis. We conduct a literature review and discuss the difficulties of diagnosis and the management of this clinical situation.
Introduction: Infarction is a very rare complication of fibroadenoma. Diagnosis of such a situation is not easy.
Case Presentation: 23-year-old woman with a painful tumor of the right breast with mild erythema at the periareolar region. Breast ultrasound shows a heterogeneous lesion of 31×30 mm, in the retroareolar right breast with well-defined borders, and does not present vascular flow inside. Antibiotic treatment was administered without improvement. The breast ultrasound was repeated with no significant changes. Surgical removal of a well-encapsulated cystic lesion was performed. The patient was discharged the same day of surgery, and her postoperative evolution was correct. Histopathologic evaluation revealed an infarcted fibroadenoma.
Conclusion: Breast ultrasound could be very useful in the diagnosis of infarcted fibroadenoma; treatment consists of local excision of the lesion.
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