Amiodarone versus a β-blocker to prevent atrial fibrillation after cardiovascular surgery

Use of vitamins C and E as a prophylactic therapy to prevent postoperative atrial fibrillation

“…Despite its universal use in the prevention of POAF, amiodarone has important disadvantages, such as serious side effects (pulmonary fibrosis) and several pharmacological interactions. Moreover, amiodarone effectiveness in preventing POAF is comparable to carvedilol, being both better than classic beta-blockers such as atenolol or propanolol [108]. Although vitamins C and E have demonstrated to be as effective as other therapies in preventing AF, the evidence regarding specifically POAF is quite limited.…”

Atrial fibrillation post-cardiac surgery: changing perspectives

“…However, the combination of amiodarone and metoprolol after cardiac surgery has been demonstrated to be more effective than metoprolol alone in the prevention of AF 23 . In one study, amiodarone even tended to be superior over propranolol for AF prevention 25 . However, this effect may in part be attributable to the fact that 42% of the patients in the amiodarone group continued to use beta-blockers.…”

Efeitos da estimulação temporária atrial direita na prevenção da fibrilação atrial no pós-operatório de revascularização do miocárdio com circulação extracorpórea

“…Pharmacological and non-pharmacological measures have been studied, among them, the prophylactic administration of beta-blockers [24][25] of unquestionable value that has been recommended in the practice guidelines for the management of patients with AF, and the use of amiodarone, but recommended for reversion of postoperative AF and in the underlying prophylaxis of this complication [26][27][28].…”