Amiodarone induced pneumonitis and hyperthyroidism: case report

Abstract

IntroductIon The use of medications is always associated with a risk of development of adverse effects, either well known and documented in available data, or completely unexpected. It is estimated that drug-induced adverse effects account for 5-7%, and in the elderly even for 10%, of all hospitalizations and are responsible for 0.15-0.3% of inpatient deaths. 1 Undesirable effects of therapy often cannot be avoided, therefore the risk of their occurrance should be kept in mind, which allows establishing early diagnosis and implementation of the adequate management. case report A 56-year-old locksmith, abusing alcohol and smoking cigarettes, with no previous history of chronic therapy, was admitted to the Department of Neurology with the rapid onset of speech and gait disorders. On admission the patient was in a moderately severe condition. Neurological examination demonstrated mixed sensomotor aphasia, profound right-sided paresis and positive Babiński's sign on the right side. The computed tomography (CT) of the brain showed features of a hemorrhagic stroke of the left hemisphere. The chest X-ray did not reveal any new onset consolidations, and function of the pulmonary circulation was normal. The ECG showed a regular sinus rhythm, with

Amiodaron i tarczyca

“…In spite of AMIO-induced thyroid disorder, it is important to remember other side effects of this medication (Table 2) because particularly pulmonary and liver toxicity may aggravate the course of AIT [29].…”

“…Należy również pamiętać o pozatarczycowych działaniach ubocznych AMIO (tab. II), ponieważ w szczególności powikłania płucne i wątrobowe mogą pogarszać przebieg AIT [29].…”