Aminopeptidase N Activatable Nanoprobe for Tracking Lymphatic Metastasis and Guiding Tumor Resection Surgery via Optoacoustic/NIR-II Fluorescence Dual-Mode Imaging

Biomimetic dual-responsive bioengineered nanotheranostics for intracellular cascade-synthesizing chemo-drugs and efficient oncotherapy

“…29 Moreover, NIR fluorescence self-imaging can provide precise information for investigating the in vivo behaviors of nanotheranostics and for guiding the therapeutic effect to optimize therapy. 41 Based on the above considerations, to further explore the tumor accumulation situation and timing of RBCs@ICG-DHN, in vivo NIR fluorescence self-imaging was performed on 4T1 tumor-bearing nude mice at predesigned time intervals after intravenous injection. As shown in Fig.…”

Recent advances in activatable NIR-II organic fluorophores for biomedical applications

“…Subsequently, the precise localization of lesions and their synchronous treatment play a crucial part in human health if abnormalities were discovered; however, the process remains challenging due to the complex physiological environment. 63 Fortunately, activatable NIR-II organic fluorescent probes can offer researchers with convenience and effectiveness to analyze and diagnose the related diseases. To date, a variety of activatable NIR-II organic fluorescent probes have been developed, and well applied in biosensing, bioimaging and also therapeutics.…”

A near-infrared fluorescent probe for detection of H2S and its application in monitoring meat freshness and plant growth under aluminium-induced stress

“…Fluorescent probes have gained widespread application in various areas such as food examination, biological imaging, and environmental monitoring due to their high selectivity, non-destructive analysis, and excellent compatibility. 5–13 Several mechanisms for designing fluorescent H 2 S probes have been successfully created, including H 2 S-mediated reductions of azides or nitro groups to amino groups, copper sulfide precipitation reactions, and the combination of nucleophilic reactions and thiolysis of leaving groups. 3,14,15 In particular, the last approach, which was developed by Feng and coworkers, 15 exhibits fast response and high sensitivity.…”