Amino-acid malabsorption and intestinal leakage of plasma-proteins in young chicks infected with Eimeria acervulina

Joyner, L. P.; Patterson, D. S. P.; Berrett, Sylvia; Boarer, C. D. H.; Cheong, F. H.; Norton, C. C.

doi:10.1080/03079457508418129

Cited by 7 publications

(11 citation statements)

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“…In addition, Ruff & Wilkins (1980) found that overall absorptive capacity of L-methionine did not change, although there were differences in absorption capacity of the affected and non-affected intestinal areas of the Eimeria acervulina-infected broilers. Reduced net intestinal N uptake might also be a result of leakage of plasma proteins into the intestinal lumen (Joyner et al 1975). In addition, N release in urine was increased as shown by increased uric acid concentrations in excreta of infected animals in Expt 2.…”

Section: Discussionmentioning

confidence: 99%

Interaction between nutrition and Eimeria acervulina infection in broiler chickens: development of an experimental infection model

1996

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In three experiments broiler chickens were inoculated with sporulated Eimeria acervulina oocysts at 18 d of age. Feed intake, body-weight gain, brush-border enzyme activities, fat digestion, protein digestion and protein retention were measured. Body-weight gain was reduced during the acute phase of the infection and increased during the recovery phase of the infection. Feed intake was decreased on day 4 and day 5 postinfection (PI) and increased from day 7 to day 11 PI. Maltase (EC 3.2.1.20) and sucrase (EC 3.2.1.48) activities were decreased on day 5 PI in all intestinal segments. In Expts 2 and 3, however, maltase activity was increased in the ileum. Fat digestion was decreased from day 2 to day 11 PI. N digestion and retention were decreased from day 2 to day 11 PI.

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Section: Discussionmentioning

confidence: 99%

Interaction between nutrition and Eimeria acervulina infection in broiler chickens: development of an experimental infection model

1996

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“…Coccidiosis usually increases the passage time of digesta during the acute phase (Schildt & Herrick, 1955;Aylott et al ., 1968). Only Joyner et al . (1975) concluded that gut passage time is decreased by E. acervulina infection.…”

Section: Coccidiosesmentioning

confidence: 99%

“…Intestinal leakage of plasma proteins. Increases in mucosal permeability are indicated by leakage of plasma proteins (Preston-Mafham & Sykes, 1967b;Rose & Long, 1969;Enigk et al ., 1970;Joyner et al ., 1975). Leakage due to E. acervulina is caused by the sexual stages damaging the mucosa (Schalm et al ., 1975;Shane et al ., 1985).…”

Section: Coccidiosesmentioning

confidence: 99%

Intercurrent coccidiosis and necrotic enteritis of chickens: rational, integrated disease management by maintenance of gut integrity

Rb¹

2005

Avian Pathology

419

319

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Coccidiosis and necrotic enteritis (NE) are globally common, sometimes intercurrent, diseases of poultry. The risk of NE, due to the Gram-positive bacterium Clostridium perfringens, has increased in recent years because of the voluntary or legally required withdrawal of the use of certain in-feed antibiotic growth promoters with anticlostridial activity. In-feed ionophorous anticoccidial drugs incidentally also possess anticlostridial activity. Such ionophores, although not banned, are usually precluded when live anticoccidial vaccines are used, potentially increasing yet further the risk of NE. This review provides information for the design of rational, integrated management strategies for the prevention and control of coccidiosis and NE in chickens by maintaining gut integrity. Because of differences in local availability of feed ingredients and national legislations regarding antibiotic growth promoters and anticoccidial vaccine licensing, no universal strategy is applicable. The diseases and their interactions are described under the headings of forms of disease, diagnosis, sources of infection, pathophysiological effects, predisposing factors, and control methods. Elements of gut integrity, which influences host predisposition and clinical responses to disease, include physical development, immune competence, gut enzyme activity, mucin production, gut flora and epithelial damage. Experimental studies of coccidiosis and NE are compared, and where possible reconciled, with field observations. Gaps in knowledge and necessary further experiments are identified. Insights are provided regarding interactions between coccidiosis, NE, and the use of live anticoccidial vaccines. Recent changes in NE prevalence in commercial flocks, and their possible causes, are discussed. The necessarily wide range of topics reviewed emphasizes the enormous complexity of this disease combination, and indicates the importance of a multidisciplinary approach in order to reduce its harmful impact on the world's poultry industry.

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“…Coccidiosis damages intestinal epithelial morphology and reduces nutrient digestibility and performance of broiler chickens (15,16). Moreover, the reduction of minearal absorption, especially in the duodenum, caused by coccidiosis might influence on bone development during grower phase.…”

Section: Introductionmentioning

confidence: 99%

Effects of Inorganic Zn and Cu Supplementation on Gut Health in Broiler Chickens Challenged With Eimeria spp.

et al. 2020

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An experiment was conducted to evaluate the effect of different levels of inorganic copper and zinc on growth performance, intestinal permeability, intestinal lesion scores, oocyst shedding, antioxidant properties and bone quality in broilers challenged with Eimeria spp. A total of 360 d-old male Cobb broiler chickens were housed in floor cages for 12 days at the Poultry Research Center. At 12 days of age, birds were placed in grower Petersime batteries and distributed in a completely randomized design with 10 birds per cage, six replicates per treatment, and six treatments. There were six corn-soybean meal-based dietary treatments: non-challenged control (NC), challenged control (CC), 100 ppm Cu (100 Cu), 150 ppm Cu (150 Cu), 80 ppm Zn (80 Zn), and 100 ppm Zn (100 Zn). Broilers received the treatment diets for 9 days (12-20d). Birds, except NC, were challenged with Eimeria maxima (50,000 oocysts/bird), Eimeria tenella (50,000 oocysts/bird), and Eimeria acervulina (250,000 oocysts/bird) on 14d. On 20d, the growth performance was recorded, and one bird/cage was used for analysis of intestinal permeability, antioxidant properties and bone quality. Lesion score was recorded at 20 days of age in eight birds/cage. The means were subjected to ANOVA and, when significant, compared by Duncan's test. Intestinal permeability was significantly improved when birds received the 100 Zn diet (P < 0.05). In addition, lesion scores on duodenum were reduced when broilers received diets 150 Cu as compared to CC diet (P < 0.05). However, growth performance was not positively influenced by inclusion of inorganic minerals as compared to the NC diet. Furthermore, activity of superoxide dismutase and bone quality were not affected, whereas glutathione status was improved with mineral supplementation in all groups. This study showed that Cu and Zn supplementation improves intestinal integrity during the Eimeria spp. infection, suggesting that Cu and Zn supplementation would be a potential strategy to reduce detrimental effects of Eimeria infection in broilers.

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Amino-acid malabsorption and intestinal leakage of plasma-proteins in young chicks infected with Eimeria acervulina

Cited by 7 publications

References 0 publications

Interaction between nutrition and Eimeria acervulina infection in broiler chickens: development of an experimental infection model

Interaction between nutrition and Eimeria acervulina infection in broiler chickens: development of an experimental infection model

Intercurrent coccidiosis and necrotic enteritis of chickens: rational, integrated disease management by maintenance of gut integrity

Effects of Inorganic Zn and Cu Supplementation on Gut Health in Broiler Chickens Challenged With Eimeria spp.

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