Ameloblastic sarcoma in the maxilla.Report of a case

Pindborg, J. J.

doi:10.1002/1097-0142(196009/10)13:5<917::aid-cncr2820130509>3.0.co;2-w

Cited by 37 publications

(3 citation statements)

References 6 publications

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“…(4-6,9-13,16-113). Papers describing clinicopathological features similar to those described for AFS were included in the first instance (4,5,(9)(10)(11)(12)(13)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(28)(29)(30)32,(34)(35)(36)(37)(38)(39)42,43,(67)(68)(69)(70)(71)(72)(74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86)(87)(88)(89)91,…”

Section: Systematic Literature Reviewmentioning

confidence: 99%

Ameloblastic Fibrosarcoma: A Case Report and Literature Review

et al. 2017

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Here is described a case of ameloblastic fibrosarcoma (AFS) affecting the posterior mandible of a woman who was treated surgically and recovered without signs of recurrence or metastasis after 12 years of follow-up. Tumor sections were immunostained for cell cycle, epithelial and mesenchymal markers. Immunohistochemical analysis evidenced high Ki-67 positivity in stromal cells (mean of 20.9 cells/High power field). Epithelial cells displayed strong positivity for p53, p63 and cytokeratin 19. In addition to the case report, a systematic review of current knowledge is presented on the AFS's clinical-demographic features and prognostic factors. Based on the review, 88/99 cases were diagnosed as AFS, 9/99 as ameloblastic fibro-odontosarcoma and 2/99 as ameloblastic fibrodentinosarcoma. All these lesions displayed very similar clinical-demographic and prognostic features. Moreover, the review provided evidence that first treatment, regional metastasis, distant metastasis and local recurrence were significant prognostic values for malignant odontogenic mesenchymal lesions. Based on the findings, segregation among ameloblastic fibrosarcoma, ameloblastic fibrodentinosarcoma and ameloblastic fibro-odontosarcoma seems illogical, considering all these lesions have similar predilections and outcomes.

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Section: Systematic Literature Reviewmentioning

confidence: 99%

Ameloblastic Fibrosarcoma: A Case Report and Literature Review

et al. 2017

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“…At the same time there exist descriptions [75] of fibro-odontoma transformation into ameloblastic fibrosarcoma. The differential diagnosis should be made with 1) osteoid osteoma which does not provoke cortex disintegration, but generates expansion; 2) multiple myeloma [20]; 3) ameloblastic sarcoma (a variety of the former, [76] constituted by odontogenic tissue and a malignant mesodermal component [77]) ; 4) ameloblastic fibrosarcoma [48] ; 5 ) fibromyxosarcoma, composed of fibroblasts intermixed with collagen fibers and reticulin [78]; 6) neurogenk fibrosarcoma [79], 7) parosteal fibrosarcoma with a greater evolution and somewhat similar to that of the soft tissues [SO] ; and 8) fibroblastic osteosarcoma [SO].…”

Section: Batsakis Et Al [8] Recognize Four Anatomical Varietiesmentioning

confidence: 99%

Sarcomas of the jaw

Yoel¹,

Aguilar²,

Simkin³

et al. 1987

Seminars in Surgical Oncology

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A retrospective analysis is made of 61 patients with clinical and histological diagnosis of pure sarcomas of the jaw treated between 1950 and 1984. Surgery was the treatment of choice in 41 cases. Biopsy or palliative treatment were undertaken in the remaining patients. Twenty-four cases relapsed before 12 months, and 12 relapsed before 3 years. Twenty-four died before 12 months, nine before 2 years, and three after 2 years. At present there is no evidence of disease in eight patients: three out of 25 fibrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), three out of 15 chondrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), and two out of 15 osteosarcomas (one more than 18 years). The prognosis is gloomy. However, an early diagnosis and radical surgery contribute to an improvement in the course of the disease.

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“…If the mesenchymal stroma of an ameloblastic fibroma is affected, the recurrent tumor may transform into AFS. [ 4 ] However, AFS can also originate de novo. [ 5 ] Muller et al .…”

Section: Introductionmentioning

confidence: 99%