Abstract:Background: Paracetamol, is the most widely used over-the-counter analgesic and antipyretic medication in the world, which has no adverse effect at therapeutic dosages. But in high doses causes renal failure. Objectives: The current study was designed to investigate paracetamol toxic effects upon the kidney and oxidative stress after repeated oral dose and evaluate possible protective effect of alpha lipoic acid when co-administered with and after paracetamol. Methods: forty eight white albino rats were divide… Show more
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