Ameliorative effect of dietary milk-derived sphingomyelin concentrates on atopic-like dermatitis in NC/Nga mice

Takeshima, Kazunori; Mori, Yasutane; Sakai, Fumihiko; Haruta-Ono, Yuko; Kadooka, Yukio; Yagasaki, Kazumi; Miura, Yutaka

doi:10.1016/j.jff.2014.03.001

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…Dietary milk‐derived SM concentrate (SPC) was found to ameliorate the clinical score of atopic‐like induced dermatitis in male NC/Nga mice, to reduce splenocyte production of interleukin‐6 and to significantly lower the numbers of infiltrated and de‐granulated mast cells (Takeshima et al . 2014). This suggests that dietary SPC suppressed systemic and peripheral inflammation.…”

Section: Nutritional and Health Benefits Of Mfgmmentioning

confidence: 99%

Milk fat globule membrane: An overview with particular emphasis on its nutritional and health benefits

El-Salam

El-Shibiny

2020

Int J of Dairy Tech

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Milk fat globule membrane (MFGM) is a minor milk constituent composed of a large number of polar lipid (PL) classes and proteins organised in a tri-layer structure. The MFGM PLs and proteins have a wide range of nutritional and health benefits. Animal and human studies have shown that consumption of MFGM preparations has beneficial effects on brain development and function and physical performance, particularly in the elderly. MFGM also improves intestinal health and skin condition, combats hypercholesterolaemia, obesity and inflammation. The present article updates the information about MFGM; particularly its nutritional and health benefits.

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Section: Nutritional and Health Benefits Of Mfgmmentioning

confidence: 99%

Milk fat globule membrane: An overview with particular emphasis on its nutritional and health benefits

El-Salam

El-Shibiny

2020

Int J of Dairy Tech

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“…It is known that SM is not only a major lipid in mammalian cells but also an important component of lipid membrane rafts (Manni et al, 2018). Additionally, SM plays important roles in lipid metabolism and anti‐inflammatory responses (Norris et al, 2019; Takeshima et al, 2014). In present study, SM and Cer levels were significantly higher in the NAM group than the control group.…”

Section: Discussionmentioning

confidence: 99%

Nicotinamide supplementation alters plasma lipidomic profiles of peripartal dairy cows

Huang¹,

Cui

Wei

et al. 2023

Animal Science Journal

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Fatty liver syndrome, a common health problem in dairy cows, occurs during the transition from pregnancy to lactation. If the energy supplied to the cow's body cannot meet its needs, a negative energy balance ensues, and the direct response is fat mobilization. Nicotinamide (NAM) has been reported to reduce the nonesterified fatty acid concentration of postpartum plasma. To study the biochemical adaptations underlying this physiologic dysregulation, 12 dairy cows were sequentially assigned to a NAM (45 g/day) treatment or control group. Blood samples were collected on day (D) 1 and D21 relative to parturition. Changes to the plasma lipid metabolism of dairy cows in the two groups were compared using lipidomics. There were significant increases in plasma sphingomyelins d18:1/18:0, d18:1/23:0, d18:1/24:1, d18:1/24:0, and d18:0/24:0 in the NAM group on D1 relative to parturition. In addition, fatty acids 18:2, 18:1, 18:0, 16:1, and 16:0 were obviously decreased on D21 relative to calving. This research has provided insights into how NAM supplementation improves lipid metabolism in perinatal dairy cows.

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Nutritional Significance of Milk Lipids: From Bioactive Fatty Acids to Supramolecular Structures Impacting Metabolism

Guillocheau

Milard

Rioux

et al. 2020

Advanced Dairy Chemistry, Volume 2

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Ameliorative effect of dietary milk-derived sphingomyelin concentrates on atopic-like dermatitis in NC/Nga mice

Cited by 3 publications

References 30 publications

Milk fat globule membrane: An overview with particular emphasis on its nutritional and health benefits

Milk fat globule membrane: An overview with particular emphasis on its nutritional and health benefits

Nicotinamide supplementation alters plasma lipidomic profiles of peripartal dairy cows

Nutritional Significance of Milk Lipids: From Bioactive Fatty Acids to Supramolecular Structures Impacting Metabolism

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