Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension

Qin, Tingli; Jiang, Hong; Yuan, Jingping; Yuan, Ke; Sun, Ning; Wang, Ji‐Guang; Zhu, Jiaan

doi:10.1177/0300060514548288

Cited by 9 publications

(8 citation statements)

References 43 publications

(84 reference statements)

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“…Those findings are consistent with our results. Tingli Qin et al concluded that in patients with grade 1/grade 2 essential hypertension, ambulatory arterial stiffness index (AASI) shows a significant correlation with ambulatory pulse pressure, which is quite similar to our study results [18].…”

Section: Arterial Stiffness Parameterssupporting

confidence: 92%

Predictors of Arterial Stiffness Amongst the 24-Hour Ambulatory Blood Pressure Variables in Hypertensive Patients

Bhandari¹,

Sharma²,

Shah³

et al. 2020

Cureus

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Section: Arterial Stiffness Parameterssupporting

confidence: 92%

Predictors of Arterial Stiffness Amongst the 24-Hour Ambulatory Blood Pressure Variables in Hypertensive Patients

Bhandari¹,

Sharma²,

Shah³

et al. 2020

Cureus

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“…The relationship between AASI and systolic blood pressure dipping status has only been previous examined in a few studies with conflicting results [10,12]. We found that AASI values were progressively and significantly higher in non-dippers and reverse dippers versus normal dippers.…”

Section: Discussionmentioning

confidence: 58%

“…It would be expected that as a surrogate of arterial stiffness AASI would be linked to blood pressure dipping status, vascular inflammation and adverse cardiovascular events. However, there have been few studies that have examined the relationship between AASI and blood pressure dipping [10][11][12] and none to investigate its links to inflammation. Whilst increasing AASI has been linked to adverse cardiovascular outcomes and worsening renal function these links and its relative benefits over traditional ABPM measures remain controversial [8,13,14].…”

Section: Open Accessmentioning

confidence: 99%

The relationship between ambulatory arterial stiffness, inflammation, blood pressure dipping and cardiovascular outcomes

Boos

Toon

Almahdi

2021

BMC Cardiovasc Disord

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Background The ambulatory arterial stiffness index (AASI) is an indirect measure of arterial stiffness obtained during ambulatory blood pressuring monitoring (ABPM). Its relationship to nocturnal blood pressure dipping status and major adverse cardiovascular events (MACE) are controversial and its association with vascular inflammation has not been examined. We aimed to investigate the relationship between the AASI, inflammation and nocturnal blood pressure dipping status and its association with MACE. Methods Adults (aged 18–80 years) who underwent 24-h ABPM for the diagnosis of hypertension or its control were included. The inflammatory markers measured were the neutrophil–lymphocyte (NLR), platelet-lymphocyte (PLR) and monocyte-lymphocyte ratios (MLR). The primary MACE was a composite of cardiovascular death, acute limb ischaemia, stroke or transient ischaemic attack (TIA) or acute coronary syndrome. Results A total of 508 patients (51.2% female) aged 58.8 ± 14.0 years were included; 237 (46.7%) were normal-dippers (≥ 10% nocturnal systolic dip), 214 (42.1%) were non-dippers (0–10% dip) and 57 (11.2%) were reverse-dippers (< 0% dip). The AASI was significantly higher among reverse (0.56 ± 0.16) and non-dippers (0.48 ± 0.17) compared with normal dippers (0.39 ± 0.16; p < 0.0001) and correlated with the NLR (r = 0.20; 95% CI 0.11 to 0.29: < 0.0001) and systolic blood pressure dipping % (r = − 0.34; − 0.42 to − 0.26: p < 0.0001). Overall 39 (7.7%) patients had ≥ 1 MACE which included a total of seven cardiovascular deaths and 14 non-fatal strokes/TIAs. The mean follow up was 113.7 ± 64.0 weeks. Increasing NLR, but not AASI or systolic dipping, was independently linked to MACE (overall model Chi-square 60.67; p < 0.0001) and MLR to cardiovascular death or non-fatal stroke/TIA (overall model Chi-square 37.08; p < 0.0001). Conclusions In conclusion AASI was associated with blood pressure dipping and chronic inflammation but not independently to MACE. The MLR and NLR were independent predictors of MACE.

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“…According to the COMMIT (Community Intervention Trial) criteria, smoking is defined when the patient is a current smoker and has smoked at least 100 cigarettes until now. Nonsmoking determination is when the patient has never smoked or used to smoke but has stopped for at least the last 5 years 9 . Exercise is when doing physical activity regularly, i.e., regular daily exercise (≥5 days/week for more than 30 minutes each), including walking or playing a sport.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of combination of perindopril and indapamide on ambulatory arterial stiffness index in Vietnamese patients with primary hypertension

Tran¹,

Huynh²,

Ngo³

et al. 2022

Pharm Sci Asia

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Hypertension is a common disease in clinical practice in many countries worldwide. There are currently about 1 billion people with hypertension, and it is estimated that by 2025, this number will reach 1.5 billion 1 . Hypertension is a deteriorative illness owing to its complications that damage target organs such as the heart, eyes, brain, and kidney, in which cardiovascular events are of particular concern. Many evidence show that arterial stiffness is an independent prognostic factor for predict-ting adverse cardiovascular outcomes in hypertensive patients 2 . The gold standard for determining arterial stiffness is to measure pulse wave velocity. Still, this method requires high-technology equipment, making it unavailable to be performed in some medical facilities, especially in the primary health care systems. Another method that correlates with the standard measurement is to evaluate by 24-hour ambulatory blood pressure monitoring. Although it is not a new method, it has adequacy of accessible opportunity, non-invasive feature, and does not require high-technical equipment. As a result, this

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Ambulatory arterial stiffness index correlates with ambulatory pulse pressure but not dipping status in patients with grade 1/grade 2 essential hypertension

Abstract: In patients with grade 1/grade 2 essential hypertension, AASI shows a significant correlation with ambulatory pulse pressure.

Cited by 9 publications

References 43 publications

Predictors of Arterial Stiffness Amongst the 24-Hour Ambulatory Blood Pressure Variables in Hypertensive Patients

Predictors of Arterial Stiffness Amongst the 24-Hour Ambulatory Blood Pressure Variables in Hypertensive Patients

The relationship between ambulatory arterial stiffness, inflammation, blood pressure dipping and cardiovascular outcomes

Effectiveness of combination of perindopril and indapamide on ambulatory arterial stiffness index in Vietnamese patients with primary hypertension

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