Ambient ozone and incident diabetes: A prospective analysis in a large cohort of African American women

Jerrett, Michael; Brook, Robert D.; White, Laura F.; Burnett, Richard T.; Yu, Jeffrey; Su, Jason; Seto, Edmund; Marshall, Julian; Palmer, Julie R.; Rosenberg, Lynn; Coogan, Patricia F.

doi:10.1016/j.envint.2016.12.011

Cited by 54 publications

(29 citation statements)

References 29 publications

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“…Racial/ethnic minorities are more likely to be of low SES and live in dense urban centers [86, 87]. Consequently, racial/ethnic minority groups, especially African Americans, have consistently shown an increased risk for CVD due to air pollution [81, 82, 51, 49, 83]. For example, Coogan et al found that higher O 3 level was associated with a 9% increased incidence of hypertension [HR=1.09 (95% CI = 1.00, 1.18)] in a large cohort of black women after a median follow-up of 11 years (total of 348,154 person-years) [49].…”

Section: Sociodemographics (Age Sex Racial/ethnic Minorities and Lomentioning

confidence: 99%

“…Many subgroups defined by sociodemographics (race/ethnicity, age, sex and SES) [81, 82, 51, 49, 83], geographic location (rural vs. urban populations) [81, 28, 84] and country economic conditions (developed vs. developing countries) [85] show striking disparities in adverse cardiovascular outcomes resulting from exposure to air pollution. Yet, all the reviews thus far have discussed this topic very broadly in the general population.…”

Section: Introductionmentioning

confidence: 99%

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Air Pollution and Cardiovascular Disease: a Focus on Vulnerable Populations Worldwide

et al. 2018

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Purpose of review: Certain subgroups defined by sociodemographics (race/ethnicity, age, sex and socioeconomic status [SES]), geographic location (rural vs. urban), comorbid conditions and country economic conditions (developed vs. developing) may disproportionately suffer the adverse cardiovascular effects of exposure to ambient air pollution. Yet, previous reviews have had a broad focus on the general population without consideration of these potentially vulnerable populations. Recent findings: Over the past decade, a wealth of epidemiologic studies have linked air pollutants including particulate matter, oxides of nitrogen, and carbon monoxide to cardiovascular disease (CVD) risk factors, subclinical CVD, clinical cardiovascular outcomes and cardiovascular mortality in certain susceptible populations. Highest risk for poor CVD outcomes from air pollution exist in racial/ethnic minorities, especially in blacks compared to whites in the U.S, those at low SES, elderly populations, women, those with certain comorbid conditions and developing countries compared to developed countries. However, findings are less consistent for urban compared to rural populations. Summary: Vulnerable subgroups including racial/ethnic minorities, women, the elderly, smokers, diabetics and those with prior heart disease had higher risk for adverse cardiovascular outcomes from exposure to air pollution. There is limited data from developing countries where concentrations of air pollutants are more extreme and cardiovascular event rates are higher than that of developed countries. Further epidemiologic studies are needed to understand and address the marked disparities in CVD risk conferred by air pollution globally, particularly among these vulnerable subgroups.

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Section: Sociodemographics (Age Sex Racial/ethnic Minorities and Lomentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Air Pollution and Cardiovascular Disease: a Focus on Vulnerable Populations Worldwide

et al. 2018

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“…Air pollution, especially traffic-related exposures, NO 2 , tobacco smoke, and particulate matter, have been associated with obesity, type 2 diabetes, and metabolic syndrome with women showing higher susceptibility than men, and children being especially susceptible [161][162][163][164]. Studies conducted in several countries, such as Europe, America, and Asia reported strong associations among exposure to air pollutants, insulin resistance, obesity, and diabetes with women overrepresented in the affected groups [165][166][167][168][169][170]. These findings have also been recapitulated in animal models, where exposure to particulate matter resulted in increased insulin resistance followed by a high-fat diet [171][172][173], and these effects were associated with inflammation triggered by mechanisms involving pulmonary oxidative stress [174].…”

Section: Outdoor Air Pollution and Lung Healthmentioning

confidence: 99%

Understanding the Intersection of Environmental Pollution, Pneumonia, and Inflammation: Does Gender Play a Role?

Silveyra¹,

Fuentes²,

Rivera³

2017

Contemporary Topics of Pneumonia

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Accumulating evidence indicates that exposure to air pollution is associated with increased mortality from respiratory disease. Exposure to ambient pollutants, such as ozone, particulate matter, sulfur dioxide, nitrogen dioxide, and other agents has been associated with decrease in lung function and immunity, and with increased rates of hospitalization for lung disease, including pneumonia. Furthermore, sex differences in frequency and severity of pulmonary disease and infection have been reported, suggesting a role of sex hormones in mediating these differences. Pneumonia, which is commonly caused by bacterial infection and subsequent lung inflammation leading to hospitalization and death, occurs at different rates in men and women. In this context, male and female hormones can have direct effects on the immunity system by binding to receptors in immune cells, and these responses can be modulated by environmental exposures. This chapter summarizes clinical, animal, and epidemiological studies linking exposure to air pollution and pneumonia in both males and females. Understanding sex-specific mechanisms in pneumonia pathogenesis and environmental responses can help in the development of more effective therapeutics and treatment options to reduce negative health outcomes in men and women.

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“…Estudou-se a relação entre concentrações de ozônio na atmosfera e incidência de diabetes tipo 2 em mulheres afro-americanas [40]. O O 3 inalado muitas vezes causa estresse oxidativo nos pulmões e leva a aumento na resistência à insulina.…”

Section: Ozônio E Saúdeunclassified

Formação De Ozônio Troposférico: Uma Revisão Da Literatura

Daemme¹,

Silva²,

Netto³

et al. 2017

Blucher Engineering Proceedings

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A crescente preocupação em relação às emissões antropogênicas e seu impacto na qualidade do ar trouxe uma discussão mais aprofundada sobre os poluentes de formação secundária, principalmente o ozônio troposférico. Esta molécula se origina de reações fotoquímicas com radiação ultravioleta e os produtos da queima de combustíveis fósseis, como os óxidos de nitrogênio (NO x ) e os compostos orgânicos voláteis (COV). Assim como o dióxido de carbono (CO 2 ) levanta discussões há décadas a respeito do aumento do efeito estufa, o ozônio (O 3 ) também demanda atenção, principalmente quanto ao meio ambiente e patologias humanas. Estudos anteriores já mostraram forte correlação entre a concentração de ozônio em grandes centros urbanos e a incidência de complicações cardiorrespiratórias e neurológicas. O presente artigo traça um panorama da atual situação dos estudos relacionados à formação do ozônio troposférico como poluente secundário proveniente das emissões veiculares. Apresenta-se uma revisão da literatura dos principais artigos que tratam do assunto no âmbito nacional e internacional, apresentando ao leitor os fundamentos do estado da arte sobre o assunto. ABSTRACT.The increasing concern about anthropogenic emission and its impact on air quality brings a deep discussion about secondary pollutants formation, mainly related to tropospheric ozone. The origin of this molecule is the photochemical reactions between products of burning fossil fuel, such as nitrogen oxides (NO x ) and volatile organic compounds (VOC), in the presence of ultraviolet radiation. Like carbon dioxide (CO 2 ) raises discussions for decades about the growing greenhouse effect, ozone also requires attention, mainly related to the environment and human pathologies. Previous studies have already shown strong correlations between ozone concentration in large urban centers and the incidence of cardiorespiratory and neurological complications. The present paper develops an overall picture of the current studies' situation associated to tropospheric ozone formation as a secondary pollutant produced from vehicular emissions. A literature review is presented, regarding the main articles related to the subject in both national and international scenario, presenting to the reader the state of the art fundamentals.

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Ambient ozone and incident diabetes: A prospective analysis in a large cohort of African American women

Cited by 54 publications

References 29 publications

Air Pollution and Cardiovascular Disease: a Focus on Vulnerable Populations Worldwide

Air Pollution and Cardiovascular Disease: a Focus on Vulnerable Populations Worldwide

Understanding the Intersection of Environmental Pollution, Pneumonia, and Inflammation: Does Gender Play a Role?

Formação De Ozônio Troposférico: Uma Revisão Da Literatura

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