Amazonian Eryngium foetidum leaves exhibited very high contents of bioactive compounds and high singlet oxygen quenching capacity

Abstract

Phenolic compounds and carotenoids profile of Amazonian Eryngium foetidum leaves and the quenching ability of their hydrophilic extract against singlet oxygen ( 1 O 2 ) were determined. Chlorogenic acid (4327 μg/g, dry basis, d.b.) was the major phenolic compound in the leaves at very high concentrations, while lutein (205 μg/g, d.b.) and β-carotene (161 μg/g, d.b.) were the major carotenoids. The extract of E. foetidum leaves was able to scavenge DPPH • (91.6% at 5 mg/mL), ABTS •+ (15.77 μM Trolox equivalent/g extract) and it exhibited high efficiency to protect tryptophan against 1 O 2 , with IC 50 at 343 μg/mL and 78% of protection at the highest tested concentration (625 μg/mL). Therefore, E. foetidum leaves can be exploited as an accessible natural source of bioactive compounds with antioxidant properties to be used by the food or pharmaceutical industries.

Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species

“…In our study, both the extracts of A. amazonicum fruits showed high efficiency as źO 2 quencher; however, the peel extract was almost five times more efficient (IC 50 = 16 µg/mL) than the pulp one (IC 50 = 76 µg/ml; Figure 2c). These extracts exhib-ited higher 1 O 2 -quenching capacity than other extracts also reported as efficient 1 O 2 -quenchers, such as the extracts with high contents of bioactive compounds obtained from leaves of Arrabidaea chica (IC 50 = 177 µg/ml; De Siqueira et al, 2019) and Eryngium foetidum (IC 50 = 343 µg/ml; Leitão et al, 2020). The inhibition of oxidative damage mediated by 1 O 2 is of paramount importance in food systems for inhibiting or delaying important oxidative reactions, such as lipid peroxidation (Choe & Min, 2006), but also in physiological systems, since excessive generation induces redox imbalance in cell physiology, causing many disorders and diseases (Schweitzer & Schmidt, 2003).…”

Eryngium foetidum L. (Apiaceae): A Literature Review of Traditional Uses, Chemical Composition, and Pharmacological Activities

“…In this sense, studies have analyzed the applications of E . foetidum and have pointed to its pharmacological potential, notably Bhavana et al [ 3 ], Forbes et al [ 13 ], Sumitha et al [ 14 ], and Leitão et al [ 15 ], confirming the bioactive and antioxidant potential of this plant.…”

“…Some essential oils are products of secondary metabolism, normally produced by aromatic plants. They are defined as complex mixtures and have high added value due to their applications in the pharmaceutical industry [ 5 , 15 ].…”

“…ey are defined as complex mixtures and have high added value due to their applications in the pharmaceutical industry [5,15]. e chemical profile of the essential oils from E. foetidum is characterized by aromatic and aliphatic aldehydes.…”

“…is species is also used in ethnomedicine, since it has shown potential application in diseases related to the gastrointestinal tract and acts as an antibacterial, analgesic, anti-inflammatory, anthelmintic, anticonvulsant, and anticancer agent, thus proving to have great ethnopharmacological importance for people [10][11][12]. In this sense, studies have analyzed the applications of E. foetidum and have pointed to its pharmacological potential, notably Bhavana et al [3], Forbes et al [13], Sumitha et al [14], and Leitão et al [15], confirming the bioactive and antioxidant potential of this plant.…”