Alzheimer&amp;#39;s Disease Prevention and Use of Traditional Plant Medicines

Xiaogang, Wang; Dubois, Raphael; James, David Adams

doi:10.2174/1570180811666140819223819

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…The mice were divided into normal control, model, Vitamin E and total glycoside groups, and all groups received different doses of various materials. The results suggested that the glycosides exhibited protective effects on the hippocampal ultrastructure, and glycosides may play a role in the delay of aging and the prevention and treatment of senile dementia via anti-oxidation ( Wang X. et al, 2015 ). Xu et al investigated the protective effect of Cistanches Herba alcohol extract on hepatic mitochondria and established an aging rat model caused by D -galactose.…”

Section: Pharmacologymentioning

confidence: 99%

Cistanches Herba: A Neuropharmacology Review

Yang

Huang

2016

Front. Pharmacol.

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Cistanches Herba (family Orobanchaceae), commonly known as “desert ginseng” or Rou Cong Rong, is a global genus and commonly used for its neuroprotective, immunomodulatory, anti-oxidative, kidney impotence, laxative, anti-inflammatory, hepatoprotective, anti-bacterial, anti-viral, and anti-tumor effects in traditional herbal formulations in North Africa, Arabic, and Asian countries. The major bioactive compound present in this plant is phenylethanoid glycosides. In recent years, there has been great important in scientific investigation of the neuropharmacological effects of the bioactive compounds. The in vitro and in vivo studies suggests these compounds demonstrate neuropharmacological activities against a wide range of complex nervous system diseases which occurs through different mechanisms include improving immunity function and kidney aging, anti-lipid peroxidation, scavenging free radical, inducing the activation of caspase-3 and caspase-8. This review aims to summaries the various neuropharmacological effects and mechanisms of Cistanches Herba extracts and related compounds, including its efficacy as a cure for Alzheimer’s disease and Parkinson’s disease with reference to the published literature. Which provides guidance for further research on the clinical application of Cistanches Herba.

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Section: Pharmacologymentioning

confidence: 99%

Cistanches Herba: A Neuropharmacology Review

Yang

Huang

2016

Front. Pharmacol.

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“…N. tazetta occurs as far east as Kashmir and Iran [16]. Narcissus bulb mostly contained alkaloids like galantamine, [17] lycorine [18] and flavonoids such as rutin, quercetin and kaempferol, phenolic acids [19] and a glycoprotein called lectin [20].…”

Section: Introductionmentioning

confidence: 99%