Alveolar ridge preservation techniques: a systematic review and meta‐analysis of histological and histomorphometrical data

Abstract

With the limitations due to the features of the selected papers, no major histological and histomorphometrical differences arose among different procedures or when compared to spontaneous healing. Thus, it might be argued that in preserved sites it is unnecessary to wait over 3 to 4 months prior to implant insertion.

The effect of combined Moringa oleifera and demineralized freeze-dried bovine bone xenograft on the amount of osteoblast and osteoclast in the healing of tooth extraction socket of Cavia cobaya

“…Accelaretion of bone regeneration mechanically might be caused by combination substanced which acts as scaffold, stabilizing blood clot and preventing epithelia from growing inward the socket, while biologically the subtances provide extra minerals. 37 Combination of subtances could be caused resorption and gradation in formation of new bone so that enabling osteocompetent penetration and endothelial cells and vascularization in order to accelerate new bone formation. 38 It can be concluded that the combination of Moringa oleifera leaf extract and DFDBBX at 2% cocentration can increase the number of osteoblasts and decrease osteoclasts in the healing of tooth extraction sockets of cavia cobaya…”

Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study

“…Because the best period to preserve the alveolar ridge is at the time of extraction [6,10,11], extraction socket preservation (ESP) procedure has been proposed as a mean of counteracting post-extraction volume loss [12-14]. Non-absorbable and absorbable membranes with or without graft materials, have been used for ESP to maintain the dimensions of the alveolar ridge following extraction [15]. The use of membrane alone in ESP has been translated by the conception of guided bone regeneration (GBR) [16], to exclude soft tissues from filling the osseous defect, and thus allowing the cells with osteogenic potential to colonize the wound [17-20].…”

Absorbable collagen sponges loaded with recombinant bone morphogenetic protein 9 induces greater osteoblast differentiation when compared to bone morphogenetic protein 2

“…The use of ACS shaped in cylindrical format has been utilized in modern dentistry to facilitate wound healing in extraction sockets. Although numerous scientific reports have now documented the effects of tooth loss on dimensional changes of alveolar bone (Araújo & Lindhe, 2005; Chappuis et al, 2013; De Risi et al, 2015; Jambhekar et al, 2015; Moraschini & Barboza, 2016; Morjaria et al, 2014; Spagnoli & Choi, 2013; Tan et al, 2012), there remains a lack of options to predictably regenerate lost bone following tooth loss. For these reasons, a variety of treatment options and various biomaterials have been investigated to minimize bone loss following tooth extraction (Bayat et al, 2015; Brkovic et al, 2008; Brkovic et al, 2012; Coomes et al, 2014; Fiorellini et al, 2005; Mardas et al, 2010; Mardas et al, 2011; Misch, 2010; Wallace, 2015; Wallace et al, 2014).…”

“…Many reports over the past decade have attempted to minimize these effects via a variety of procedures including collagen barrier membranes, bone grafting materials and growth factors (Bayat, Momen Heravi, Mahmoudi, & Bahrami, 2015; Brkovic et al, 2008; Brkovic et al, 2012; Coomes et al, 2014; Fiorellini et al, 2005; Mardas, Chadha, & Donos, 2010; Mardas, D'Aiuto, Mezzomo, Arzoumanidi, & Donos, 2011; Misch, 2010; Wallace, 2015; Wallace, Pikos, & Prasad, 2014). Despite this, tooth loss remains a prominent challenge, and no single therapy has been shown capable of predictably preventing dimensional bone‐changes following extraction (De Risi, Clementini, Vittorini, Mannocci, & De Sanctis, 2015; Jambhekar, Kernen, & Bidra, 2015; Moraschini & Barboza, 2016; Morjaria, Wilson, & Palmer, 2014; Spagnoli & Choi, 2013; Tan, Wong, Wong, & Lang, 2012). …”