Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration

Abstract

Gulf War Syndrome is a multi-system disorder afflicting many veterans of Western armies in the 1990-1991 Gulf War. A number of those afflicted may show neurological deficits including various cognitive dysfunctions and motor neuron disease, the latter expression virtually indistinguishable from classical amyotrophic lateral sclerosis (ALS) except for the age of onset. This ALS "cluster" represents the second such ALS cluster described in the literature to date. Possible causes of GWS include several of the adjuvants in the anthrax vaccine and others. The most likely culprit appears to be aluminum hydroxide. In an initial series of experiments, we examined the potential toxicity of aluminum hydroxide in male, outbred CD-1 mice injected subcutaneously in two equivalent-tohuman doses. After sacrifice, spinal cord and motor cortex samples were examined by immunohistochemistry. Aluminum-treated mice showed significantly increased apoptosis of motor neurons and increases in reactive astrocytes and microglial proliferation within the spinal cord and cortex. Morin stain detected the presence of aluminum in the cytoplasm of motor neurons with some neurons also testing positive for the presence of hyper-phosphorylated tau protein, a pathological hallmark of various neurological diseases, including Alzheimer's disease and frontotemporal dementia. A second series of experiments was conducted on mice injected with six doses of aluminum hydroxide. Behavioural analyses in these mice revealed significant impairments in a number of motor functions as well as diminished spatial memory capacity. The demonstrated neurotoxicity of aluminum hydroxide and its relative ubiquity as an adjuvant suggest that greater scrutiny by the scientific community is warranted.

A simplified superovulation protocol using split-single administration of Folltropin®-V in hyaluronan: application to purebred sheep

“…Although these agents were effective at eliciting a slow release of FSH to induce a superovulatory response, in humans, PG and polyvinylpyrrolidone have caused allergic reactions (Catanzaro and Smith 1991;Gonzalo et al 1999;Yoshida et al 2007;Marques et al 2011), while aluminum hydroxide induced neuropathological reactions and macrophagic myofascitis (Gherardi et al 2001;Shaw and Petrik 2009). In contrast, there have been no reports of side effects from HA administered in mammals.…”

How Silencing of Dissent in Science Impacts Woman. The Gardasil® Story

“…Aluminum has been linked to a number of disorders of the nervous system GI tract including but not limited to multiple sclerosis, Crohn's disease [84], Gulf War Syndrome, Alzheimer's disease [85], autism and ALS [86]. So, without the use of a true placebo can the true safety of Gardasil ® be evaluated?…”

The meaning of aluminium exposure on human health and aluminium-related diseases

“…A subset of veterans of the 1991 Persian Gulf War developed a severe motor neuron disease, virtually indistinguishable from classical amyotrophic lateral sclerosis (ALS), except for the age of onset (94) . Whereas numerous environmental factors have been linked to the origin of GWS, the role of the adjuvant aluminium hydroxide associated to the multiple vaccines that Western army soldiers underwent during the months before their departure to the Persian Gulf War has come under increasing scrutiny (95) .…”