Aluminium levels in Italian diets and in selected foods from aluminium utensils

Gramiccioni, L.; Ingrao, G.; Milana, Maria Rosaria; Santaroni, Paolo; Tomassi, G.

doi:10.1080/02652039609374464

Cited by 49 publications

(34 citation statements)

References 2 publications

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“…Four separate liver enzymes, including AST and ALT, which, together, are known as transaminases, ALP, which is a cholestatic liver enzyme, and LDH, are reliable indicators of liver function. AST and ALT are critical enzymes for biological processes [25] . An increase in serum AST and ALT in rats treated with AlCl 3 was in agreement with previous findings demonstrating that AlCl 3 exposure promoted liver necrosis[ 39,41,42] .…”

Section: Discussionmentioning

confidence: 99%

“…In 1989, the FAO/WHO Expert Committee on Food Additives reported that the daily intake of aluminum in children was between 2 and 6 mg, and in adults, it varied between 6 and14 mg [25][26][27] . Therefore, the daily intake of aluminum in an adult with a mean body weight 70 kg is between 0.1 and 0.2 mg kg −1 body weight.…”

Section: Determination Of Alcl 3 Daily Dosementioning

confidence: 99%

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Camel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino Rats

Al‐Hashem¹

2009

American Journal of Biochemistry and Biotechnology

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Problem statement: Aluminum chloride (AlCl 3 ) is commonly used in daily life but it can be potentially toxic. Therefore, the present study was carried out to investigate the protective effects of camel's milk against aluminum-induced biochemical alterations and oxidative stress in the liver and kidney of white albino rats. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: a control group treated with normal saline, the AlCl 3 -treated group and the camel's milk-AlCl 3 -treated group. The AlCl 3 treated group received 0.5 mg kg −1 of AlCl 3 orally. The camel's milk-AlCl 3 -treated group was fed 1 mL of fresh camel's milk 10 minutes prior to the administration of oral AlCl 3 . All rats were treated every day for 30 days. Liver and kidney biochemical serum parameters were analyzed. Lipid peroxidation, as determined by the tissue concentrations of thiobarbituric acid reactive substances (TBARS) and hydrogen peroxide (HP), and the oxidative stress status, as measured by glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) activity, were evaluated in the kidney and liver of treated rats. Results: Data showed that the oral administration of AlCl 3 resulted in statistically significant increases in the serum levels of urea, creatinine, bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), cholesterol and triglycerides; the total amount of protein and albumin were also significantly decreased. However, these parameters were within normal levels in the rats given camel's milk prior to AlCl 3 . Additionally, oral administration of AlCl 3 induced lipid peroxidation in the liver and kidney, which was indicated by a significant increase in lipid peroxidation biomarkers (TBARS and HP) and a significant decrease in the activities of GSH, SOD and CAT. In all rats treated with camel's milk before being given AlCl 3 , lipid peroxidation and oxidative stress parameters were within normal levels. Conclusion: Treatment with camel's milk prior to AlCl 3 exposure alleviates AlCl 3 -associated hazards and protects the kidney and liver from AlCl 3 toxicity.

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Section: Discussionmentioning

confidence: 99%

Section: Determination Of Alcl 3 Daily Dosementioning

confidence: 99%

Camel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino Rats

Al‐Hashem¹

2009

American Journal of Biochemistry and Biotechnology

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“…In 1989, the FAO/WHO Expert Committee on Food Additives reported that the daily intake of aluminum in children ranged between 2 and 6 mg and in adults, it varied between 6 and 14 mg [34][35][36] . Therefore, the daily intake of aluminum in an adult with a mean body weight 70 kg ranges between 0.1 mg and 0.2 mg kg −1 body weight.…”

Section: Dose Determinationmentioning

confidence: 99%

Camel’s Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat’s Testes

Al‐Hashem¹

2009

American J. of Applied Sciences

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Problem statement: The present study was carried out to examine the effectiveness of Camel's milk in alleviating aluminum chloride (AlCl 3 )-induced oxidative stress and lipid peroxidation in rat testes. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: A control group, treated with normal saline and two experimental groups, the AlCl 3 treated group and the Camel's milk-AlCl 3 treated group. The first experimental group, the AlCl 3 treated group, received 0.5 mg kg −1 of AlCl 3 orally. The second experimental group was fed 1 mL of fresh Camel's milk 10 min prior to the administration of oral AlCl 3 . All rats were treated every day for 30 days. Lipid peroxidation, as determined by testicular concentration of Thiobarbituric Acid Reactive Substances (TBARS) and Hydroperoxide (HP) levels and the oxidative stress status, as measured by glutathione (GSH) levels, Superoxide Dismutase (SOD) and Catalase (CAT) activity, were evaluated in the rat testes. Results: Oral administration of AlCl 3 induced lipid peroxidation and oxidative stress in rat testes, which was indicated by a significant increase in lipid peroxidation biomarkers (TBARS and HP) and a significant decrease in the GSH content and SOD and CAT activities. When rats received Camel's milk before being given AlCl 3 , lipid peroxidation and oxidative stress parameters were restored to normal levels. In the testes from rats fed Camel's milk TBARS and HP levels were significantly reduced and, conversely, GSH content, SOD and CAT activities were significantly increased compared to rats that received only AlCl 3 . Conclusion: Treatment with Camel's milk prior to AlCl 3 alleviates AlCl 3 -associated hazards and protects testicular tissue from AlCl 3 toxicity.

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“…It is well established that several components in orange juice migrate into polymers [24]. Aluminium surfaces can deteriorate whenever they come into contact with salty, acidic, or even neutral aqueous media [25]. Because of those corrosive effects, Al can migrate to the fruit juice and its content may be elevated in the products.…”

Section: Discussionmentioning

confidence: 99%

Levels of Major and Minor Elements in Some Commercial Fruit Juices Available in Serbia

Velimirović¹,

Mitić²,

Tošić³

et al. 2013

Trop. J. Pharm Res

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Aluminium levels in Italian diets and in selected foods from aluminium utensils

Cited by 49 publications

References 2 publications

Camel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino Rats

Camel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino Rats

Camel’s Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat’s Testes

Levels of Major and Minor Elements in Some Commercial Fruit Juices Available in Serbia

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