An emerging body of research has shed light on the efects of social-environmental factors, such as exposure to sufering, social class, and social power on prosocial orientation (i.e., empathy and compassion). This chapter aims to provide an overview of these areas of research that examined how the aforementioned social-environmental factors may accentuate or atenuate one's tendency to be prosocial. In addition, this chapter explores the theoretical implications across these areas and its potential for future research.