Altos niveles de adiposidad se asocian a un deterioro en la salud metabólica en adultos chilenos

Leiva, Ana Marı́a; Martínez, María; Durán, Eliana; Labraña, Ana María; Díaz, Ximena; Salas, Carlos; Ramírez‐Campillo, Rodrigo; Cristi-Montero, Carlos; Garrido-Méndez, Álex; Celis‐Morales, Carlos

doi:10.4067/s0717-75182017000300262

Cited by 3 publications

(3 citation statements)

References 20 publications

(23 reference statements)

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“…However, baPWV is also widely used in many studies, and baPWV is highly correlated with cfPWV and is a recognized marker of arterial stiffness (11,12). Finally, several factors, such as participant nutritional status (50,51), sedentary lifestyle (52), physical activity (30), and depression (53), were found to be associated with HGS. However, these data were unavailable in this study, so we cannot explore the potential association between those factors and HGS.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Arterial stiffness is associated with handgrip strength in relatively healthy Chinese older adults

He,

Niu,

et al. 2024

Front. Nutr.

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BackgroundIncreased arterial stiffness and low handgrip strength (HGS) are associated with poor health outcomes and are a severe health risk for older adults. However, there is limited evidence and mixed results on whether there is an association between them. Therefore, this study focused on the association between arterial stiffness and HGS in relatively healthy older adults in Beijing, China.MethodsIn 2016, 2,217 adult volunteers were recruited in Beijing. Brachial-ankle pulse wave velocity (baPWV) and the ankle-brachial index were measured using an automatic vascular profiling system. Carotid artery intima-media thickness and common carotid artery-internal diameter (CCAID) were evaluated using Doppler ultrasound, and HGS was measured with a dynamometer. Low HGS was determined using the Asian Sarcopenia Working Group 2019 criteria. Multivariate linear and logistic regressions evaluated the relationship between arterial stiffness and HGS.ResultsUltimately, 776 relatively healthy older adults (mean age 69.05 ± 6.46 years) were included. Based on the AWGS2019 criteria, 137 participants were defined as having low HGS. Compared to the normal HGS group, the low HGS group was older and had higher baPWV (p < 0.001) but lower CCAID, body mass index (BMI) and hemoglobin (Hb) (p < 0.05). The multiple linear regression analysis revealed that baPWV was negatively correlated with HGS (β = −0.173, t = −2.587, p = 0.01). Multivariate logistic regression analysis showed that baPWV and CCAID were associated with an increased risk of low HGS (odds ratio (OR) per SD increase: 1.318, p = 0.007; OR per SD increase: 0.541, p < 0.001).ConclusionArterial stiffness and HGS were significantly negatively correlated in relatively healthy Chinese older adults. Low HGS is associated with increased arterial stiffness. Encouraging exercise training to improve HGS, thereby reducing arterial stiffness and the risk of cardiovascular events, may be a simple and effective intervention.

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Section: Strengths and Limitationsmentioning

confidence: 99%

Arterial stiffness is associated with handgrip strength in relatively healthy Chinese older adults

He,

Niu,

et al. 2024

Front. Nutr.

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“…With social and economic development and noteworthy changes in people's working environment and conditions, the impact of occupational exposure on personal health is becoming ever more apparent, going beyond physical health to include mental health. For instance, prolonged sedentary behavior and overwork have been linked to an increased prevalence of obesity and cardiovascular diseases (1). Furthermore, increased work pressure and psychological burden are associated with a higher likelihood of mental health problems such as depression and anxiety (2).…”

Section: Introductionmentioning

confidence: 99%

Causality of occupational exposure on rheumatoid arthritis and ankylosing spondylitis: a two-sample mendelian randomization study

Du,

Zhang,

et al. 2023

Front. Immunol.

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ObjectiveThis study aimed to explore the potential causal link between three specific types of occupational exposure on rheumatoid arthritis (RA) and ankylosing spondylitis (AS).MethodA Two-sample Mendelian randomization (TSMR) analysis, comprising univariate MR (UVMR) and multivariate MR (MVMR) analyses, was performed to investigate the potential causal association between three types of occupational exposures, jobs involving mainly walking or standing (JWS), jobs involving heavy manual or physical work (JMP), and jobs involving shift work(JSW) on RA and AS. Genetic variants for genome-wide association studies (GWAS) of occupational exposure and AS were obtained from the UK Biobank. GWAS summary data for RA were obtained from FinnGen Biobank analysis. For UVMR, six methods of Inverse Variance Weighted (IVW), MR-Egger, Weighted Mode, Weighted Median, Simple Mode, MR pleiotropy residual sum, and outlier (MR-PRESSO) were used for the analysis. The MVMR was analyzed using the IVW model as well as the MR-Egger model.ResultsThe UVMR suggested no causal relationship between the three occupational exposure and RA [IVW: P=0.59,0.21,0.63] or AS [IVW: P=0.43,0.57,0.04], as did the bidirectional MR [IVW: P=0.73,0.70,0.16], [IVW: P=0.65,0.68,0.74]. Although unadjusted MVMR suggested a causal relationship between JMP and AS [IVW: OR = 1.01, 95% CI = 1.00- 1.02, p = 0.02], the adjusted MVMR denied this relationship and concluded that there was no causal relationship between the other occupational exposure and either RA or AS.ConclusionOur MR analysis did not establish a direct causal relationship between certain occupational exposures and either RA or AS.

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“…In some studies the results are presented as factors expanded to the Chilean national population (Garrido-Méndez et al, 2020;Troncoso-Pantoja et al, 2020b;Troncoso-Pantoja et al, 2020c;Vásquez-Gómez et al, 2020). It should be considered that in many cities of the country, evaluations are carried out every year, and that in certain places low averages of CVRF have been found in young adults, for example in glycemia, hypertension and cholesterol (Leiva et al, 2017). Therefore, it is not possible to ensure what happens in other specific local contexts of the country, at the provincial and municipal level, or in small cities.…”

Section: Introductionmentioning

confidence: 99%

Physical activity and cardiovascular risk factors of a Health Department Central-South Chile: Trend from 2015 to 2019

Castillo-Retamal¹,

Faúndez-Casanova²,

Carvalho³

et al. 2021

Journal of Human Sport and Exercise - 2021 - Spring Conferences of Sports Science

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The objective was to evaluate the trend of physical activity (PA) and cardiovascular risk factors (CVRF) in a Department of Health in Chile between 2015 and 2019. Records of people ≥15 years of age were analysed to determine the trend of PA, nutritional status, cardiometabolic diseases and lifestyles. The probability that these variables occurred over the years was calculated. A tendency to decrease in PA was found in all cases, in men and women, and an increase in CVRF for all cases and in women; between 2015 and 2019, there was a certain stability in men. Women who consulted for PA in July-September 2019 were more likely to do so compared to men (OR: 2.09, p < .001), women with obesity (OR: 1.81, p < .0001), overweight (OR: 1.91, p < .0001), hypertension (OR: 1.15, p = .01), high blood glucose (OR: 1.36, p < .0001) and smoking (OR: 2.4, p < .0001) were more likely to suffer them compared to men in April-June 2019. It is concluded that the highest and lowest periods in the cases of PA and CVRF could be known, and the probability that these occurred over time could be estimated. PA can be important for the control and treatment of CVRF.

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Altos niveles de adiposidad se asocian a un deterioro en la salud metabólica en adultos chilenos

Cited by 3 publications

References 20 publications

Arterial stiffness is associated with handgrip strength in relatively healthy Chinese older adults

Arterial stiffness is associated with handgrip strength in relatively healthy Chinese older adults

Causality of occupational exposure on rheumatoid arthritis and ankylosing spondylitis: a two-sample mendelian randomization study

Physical activity and cardiovascular risk factors of a Health Department Central-South Chile: Trend from 2015 to 2019

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