Alternatives to Enhance the Anticaries Effects of Fluoride

Delbem, Alberto Carlos Botazzo; Pessan, Juliano Pelim

doi:10.1007/978-3-319-93426-6_6

Cited by 6 publications

(6 citation statements)

References 77 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The remineralization process is affected by the decrease of the availability of calcium and fluoride ions due to the instability of β-TCP in water-based preparations. 15 Despite its ability to recover the enamel surface hardness, this explains the inferior results of BPC to remineralize the subsurface carious lesion. Conversely, the desensitizing toothpaste ESS also contains a declared content of β-TCP but in association with tetrasodium pyrophosphate and Pro-Argin/CalSeal technologies.…”

Section: Discussionmentioning

confidence: 99%

“…13,14 The evolving technology and research on the development of new products aim not only to reduce enamel demineralization but also boost the remineralizing capability of formulations, thus reducing the side effects of conventional fluoride treatments. 15 Despite these improvements, the action of fluoride in remineralization is still considered the gold standard when compared with other remineralization systems. 12,16 Changes in toothpaste formulations allowed the addition of a variety of novel active ingredients, which may affect the pH and abrasiveness of the toothpaste.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge

et al. 2020

View full text Add to dashboard Cite

Objectives This in vitro study investigated the remineralization potential of 1450 ppm, fluoride-containing toothpastes containing different active remineralization agents after cariogenic challenge with pH cycling. The enamel surface roughness after brushing and the chemical and physical characteristics of the toothpastes tested were also analyzed. Materials and Methods Fifty-six bovine enamel blocks were obtained (4 × 4 × 6 mm) and divided into three thirds: intact (untreated), demineralized (artificial caries lesion), and treated (caries lesion, pH cycling, and brushing with dentifrices). Seven commercially available fluoride toothpastes (1450 ppm F): three with anti-erosion claims ( Candida Professional [CPP], Colgate Total 12 Daily Repair [CDR], Regenerate Enamel Science [RES]); three with desensitizing claims (Bianco Pro Clinical [BPP], Elmex Sensitive [ESS], and Regenerador Diário DentalClean [RDC]); and one standard regular-fluoride toothpaste Colgate Total 12 (CTT) were selected. During pH cycling (demineralization 6 h/remineralization 18 h) for 7 days, the treated third was brushed with the different dentifrices for 10 minutes in a brushing machine before immersion in a remineralizing solution. The Knoop hardness (25 g, 10 second of the surface, and longitudinal section were then evaluated at eight depths (10 to 330 μm). Mean and percentage of surface hardness recovery (% SHR) were calculated. Surface enamel roughness (Ra) was also evaluated. The pH, %weight of particles, zeta potential, and polydispersity index of toothpaste slurries were also evaluated. Statistical Analysis Data were statistically analyzed (ANOVA/Tukey, 5%). Results The %SHR of CPP was significantly lower than the others (p < 0.05). The enamel subsurface was more effectively remineralized when treated with BPP, ESS, and RDC. The surface roughness was higher when the demineralized third was treated with CTT, RDC, and RES and after the cariogenic challenge (p < 0.05). For some of the products tested, there was no relationship between surface remineralization and subsurface remineralization. Although toothpastes CPP and RDC present the lowest %SHR Abstract Keywords ► enamel ► hardness ► roughness ► toothpaste ► tooth remineralization

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In vitro mechanistic investigations have confirmed this, demonstrating that calcium has a twenty-fold greater inhibitory effect on enamel disintegration than phosphate (31). At the same amount of super saturation, enamel remineralisation can be performed optimally with a calcium/phosphate ratio of 1.6 (32). Despite this, the Ca/P ratio in plaque fluid is approximately 0.3 (33).…”

Section: Efficacy Of Calciummentioning

confidence: 85%

Enamel remineralisation and efficacy of remineralising agents: A Review

Abbas

2022

jwmdc

View full text Add to dashboard Cite

To review current information and technology for tooth remineralisation. Searches in the "Scopus" and "Web ofKnowledge" databases, which date back to 1970s. English was the only language allowed. The study incorporatedboth original research and previously published reviews. Tooth remineralisation agents, products, and treatmentshave progressively increased in recent years due to the growing awareness of the significance of good dentalhealth among patients and general community. Both in vitro and in vivo tooth remineralisation anddemineralization research have been published regularly. Theobromine has been proposed as an effectiveremineralising agent and a viable alternative to fluorides in recent years. According to research, fluoride treatmentscan prevent dental enamel demineralization and remineralisation. An increasing number of products containingcalcium salts or calcium-based compounds have been added to oral care products to boost the delivery andretentiveness of fluoride into teeth. Calcium salts or materials, which provide an additional source of calcium,may aid in accelerating enamel remineralisation or hinder demineralization processes. These effects are possiblebecause calcium is a mineral. A new area of research inspired by bioactive materials for bone repair andregeneration, bioglass, in particular calcium silicates, shows promise for improving enamel health and is one typeof bioglass that contains calcium silicate.

show abstract

“…Instead, it is replaced with natural components such as herbs, which are characterized by anti-bacterial properties, as seen in e.g., bamboo salt [ 70 ]. Other types of toothpaste include those which contain phosphorus compounds, calcium phosphate, functionalized β-tricalcium phosphate, calcium glycerophosphate, cyclophosphates, calcium sucrose phosphate, zinc hydroxyapatite, or toothpastes with an acidic pH [ 71 , 72 ]. Recently, it has been shown that toothpaste with a potent penetration promoter, azone, and vitamin D3 may be helpful in the prevention of the common deficiencies of this vitamin.…”

Section: Discussionmentioning

confidence: 99%

Assessing Fluorosis Incidence in Areas with Low Fluoride Content in the Drinking Water, Fluorotic Enamel Architecture, and Composition Alterations

Strużycka

Olszewska

Bogusławska-Kapała

et al. 2022

IJERPH

View full text Add to dashboard Cite

There is currently no consensus among researchers on the optimal level of fluoride for human growth and health. As drinking water is not the sole source of fluoride for humans, and fluoride can be found in many food sources, this work aimed to determine the incidence and severity of dental fluorosis in Poland, in areas where a low fluoride content characterizes the drinking water, and to assess the impact of fluoride on the enamel composition and microstructure. The dental examination involved 696 patients (aged 15–25 years) who had since birth lived in areas where the fluoride concentration in drinking water did not exceed 0.25 mg/L. The severity of the condition was evaluated using the Dean’s Index. Both healthy teeth and teeth with varying degrees of fluorosis underwent laboratory tests designed to assess the total protein and fluoride content of the enamel. Protein amount was assessed spectrophotometrically while the level of fluoride ions was measured by DX-120 ion chromatography. The clinical study revealed 89 cases (12.8%) of dental fluorosis of varying severity. The enamel of teeth with mild and moderate fluorosis contained a significantly higher protein (p-value < 0.001 and 0.002, respectively) and fluoride level (p < 0.001) than those with no clinical signs of fluorosis. SEM images showed irregularities in the structure of the fluorotic enamel. An excessive fluoride level during amelogenesis leads to adverse changes in the chemical composition of tooth enamel and its structure. Moreover, dental fluorosis present in areas where drinking water is low in fluorides indicates a need to monitor the supply of fluoride from other possible sources, regardless of its content in the water.

show abstract

Alternatives to Enhance the Anticaries Effects of Fluoride

Cited by 6 publications

References 77 publications

Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge

Effects of 1450-ppm Fluoride-containing Toothpastes Associated with Boosters on the Enamel Remineralization and Surface Roughness after Cariogenic Challenge

Enamel remineralisation and efficacy of remineralising agents: A Review

Assessing Fluorosis Incidence in Areas with Low Fluoride Content in the Drinking Water, Fluorotic Enamel Architecture, and Composition Alterations

Contact Info

Product

Resources

About