Alternative therapeutic advantages of catfish bile on atopic dermatitis: protection of T cell-mediated skin disease via antioxidant activities

Lee, Do Ik; Huh, Yoon Joo; Hwang, Kwang Woo; Choi, Young In; Choi, Jaesik; Han, Sam-Yong; Gyoung, Young-Soo; Joo, Seong Soo

doi:10.1111/j.2042-7158.2011.01337.x

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…19) L-Ascorbic acid and its fatty acid esters are used as food additives, antioxidants, browning inhibitors, reducing agents, flavor stabilizers, dough modifiers, and color stabilizers. 20,21) Encapsulating L-ascorbic acid in emulsion systems is highly recommended due to its hydrophilic nature and rapid degradation in bulk aqueous systems. Both singleand double-emulsion systems are used to encapsulate L-ascorbic acid.…”

Section: ) L-mentioning

confidence: 99%

Preparation and Characterization of Water-in-Oil-in-Water Emulsions Containing a High Concentration ofL-Ascorbic Acid

Khalid

Kobayashi

Neves

et al. 2013

Bioscience, Biotechnology, and Biochemistry

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This study sought to encapsulate a high concentration of L-ascorbic acid, up to 30% (w/v), in the inner aqueous phase of water-in-oil-water (W/O/W) emulsions with soybean oil as the oil phase. Two-step homogenization was conducted to prepare W/O/W emulsions stabilized by a hydrophobic emulsifier and 30% (v/v) of W/O droplets stabilized by a hydrophilic emulsifier. First-step homogenization prepared W/O emulsions with an average aqueous droplet diameter of 2.0 to 3.0 m. Second-step homogenization prepared W/O/W emulsions with an average W/O droplet diameter of 14 to 18 m and coefficients of variation (CVs) of 18% to 25%. The results indicated that stable W/O/W emulsions containing a high concentration of L-ascorbic acid were obtained by adding gelatin and magnesium sulfate in the inner aqueous phase and glucose in both aqueous phases. L-Ascorbic acid retention in the W/O/W emulsions was 40% on day 30 and followed first-order kinetics.

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Section: ) L-mentioning

confidence: 99%

Preparation and Characterization of Water-in-Oil-in-Water Emulsions Containing a High Concentration ofL-Ascorbic Acid

Khalid

Kobayashi

Neves

et al. 2013

Bioscience, Biotechnology, and Biochemistry

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show abstract

“…AD and asthma are Th2 immunity-biased allergic inflammatory diseases [22,23], characterized by production of Th2 cytokines (IL-4, IL-5 and IL-13) and large amounts of TNF albeit little or no IL-10 [14]. As an atypical Th2 cytokine, TNF is prominent in asthmatic airways [24].…”

Section: Tslp: Function and Roles In Th2 Immunitymentioning

confidence: 99%

Thymic Stromal Lymphopoietin: A Promising Therapeutic Target for Allergic Diseases

Wang

Zhang

et al. 2012

Int Arch Allergy Immunol

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Thymic stromal lymphopoietin (TSLP), an interleukin 7-like cytokine, can trigger dendritic cell (DC)-mediated T-helper type 2 (Th2) inflammatory responses. Recent evidence demonstrates that cytokines TSLP and OX40 (CD134)/OX40 ligand seem to be important players in the maintenance of Th2 memory pool in the pathogenesis of asthma. Accumulating data reveal that the pathogenic T cells involved in asthma are likely to be inflammatory Th2 cells. TSLP is involved in the development of asthma through crosstalk with nuclear factor NF-ĸB. Progression of skin fibrosis in atopic dermatitis occurs via TSLP/TSLP receptor. TSLP-mediated dermal inflammation aggravates experimental allergic asthma. Also, TSLP polymorphisms are associated with susceptibility to asthma, atopic dermatitis, and eczema herpeticum. These findings suggest a master switch of TSLP in the initiation of allergic and adaptive inflammation through innate pathways at the epithelial cell-DC interface. The TSLP pathway is therefore a promising target for immunotherapy of allergic diseases.

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Melatonin protects mast cells against cytotoxicity mediated by chemical stimuli PMACI: Possible clinical use

Maldonado

García-Moreno

Calvo

2013

Journal of Neuroimmunology

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Alternative therapeutic advantages of catfish bile on atopic dermatitis: protection of T cell-mediated skin disease via antioxidant activities

Abstract: The results presented in this study suggest that SAB may provide functional advantages with regard to treating atopic dermatitis because of its antioxidant and immune-suppressive effects.

Cited by 4 publications

References 19 publications

Preparation and Characterization of Water-in-Oil-in-Water Emulsions Containing a High Concentration ofL-Ascorbic Acid

Preparation and Characterization of Water-in-Oil-in-Water Emulsions Containing a High Concentration ofL-Ascorbic Acid

Thymic Stromal Lymphopoietin: A Promising Therapeutic Target for Allergic Diseases

Melatonin protects mast cells against cytotoxicity mediated by chemical stimuli PMACI: Possible clinical use

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