Alterations in ocular surface and corneal thickness in relation to metabolic control in patients with chronic renal failure

Aktaş, Zeynep; Özdek, Şengül; Dinç, Umut Aslı; Akyürek, Nalân; Atalay, Veli; Güz, Galip; Hasanreısoğlu, Berati

doi:10.1111/j.1440-1797.2007.00805.x

Cited by 43 publications

(48 citation statements)

References 22 publications

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“…Most of our cases were grade-1 (57%). Aktas et al reported similar results to our study with only grade-1 calcification in 59% of patients (16). However, Dursun et al reported higher proportions, in that 63% of patients were grade-3 to 5 (4).…”

Section: Discussionsupporting

confidence: 77%

“…This difference among these studies may be associated with the duration of haemodialysis of the patients. The mean duration of haemodialysis was 3.43 years in our study, 3.6 years in Aktas et al's study but 5.0 years in Dursun et al's study (4,16). Hsiao et al also reported a significant relationship between the duration of haemodialysis and the degree of calcification (18).…”

Section: Discussionmentioning

confidence: 59%

“…Perhaps the primary cause of red eye is the irritative effect of calcifications (2,16). Red eye is the most common symptom in our patient group (83%).…”

Section: Discussionmentioning

confidence: 98%

“…In our study, only 5% of the patients were grade 2-3. This may be due to the short duration of the haemodialysis of the patients, as described in the study of Aktas et al (4,16).…”

Section: Discussionmentioning

confidence: 99%

“…Reports of their incidence vary widely in the literature, from 36% to 86%. Generally, the calcifications are located in the perilimbal conjunctiva (2,8,16,17). In our study, we found that CCC's were higher in patients with CRF, as described in the literature.…”

Section: Discussionmentioning

confidence: 99%

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Ocular Surface Findings in Chronic Renal Failure

Türkçü

Temiz

et al. 2014

Electron J Gen Med

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 59%

“…Perhaps the primary cause of red eye is the irritative effect of calcifications (2,16). Red eye is the most common symptom in our patient group (83%).…”

Section: Discussionmentioning

confidence: 98%

“…In our study, only 5% of the patients were grade 2-3. This may be due to the short duration of the haemodialysis of the patients, as described in the study of Aktas et al (4,16).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Ocular Surface Findings in Chronic Renal Failure

Türkçü

Temiz

et al. 2014

Electron J Gen Med

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Corneal and Coronary Calcification in Maintenance Hemodialysis: The Face Is No Index to the Heart

Pessoa,

Santo,

de Deus

et al. 2023

JBMR Plus

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Although the eyes are the main site of metastatic calcification in patients with chronic kidney disease (CKD), corneal and conjunctival calcification (CCC) is poorly evaluated in this population. Whether CCC correlates with coronary artery calcification remains unknown since studies so far have relied on methods with low sensitivity. Our objective was to test the relationship between CCC and coronary calcification based on tomography. This was a cross‐sectional study that included patients on maintenance dialysis. Clinical, demographic, and biochemical data (calcium, phosphorus, parathormone, alkaline phosphatase, and 25(OH)‐vitamin D) were recorded. Hyperparathyroidism was defined as parathyroid hormone (PTH) > 300 pg/mL. CCC was evaluated by anterior segment optical coherence tomography (AS‐OCT), and coronary calcium scores (Agatston method) were assessed by computed tomography. We compared no/mild with moderate/severe CCC. Twenty‐nine patients were included (49.6 ± 15.0 years, 62.1% female, on hemodialysis for 5.7 [2.7–9.4] years, 17.2% with diabetes mellitus, 75.9% with hyperparathyroidism). CCC was found in 82.7% of patients, with median scores of 9 (3, 14.5), ranging from 0 to 16. CCC was classified as absent/mild, moderate, and severe in 27.6%, 20.7%, and 51.7%, respectively. Coronary calcification was found in 44.8% of patients, with median scores of 11 (0, 464), varying from 0 and 6456. We found no significant correlation between coronary calcium scores and CCC (r = 0.203, p = 0.282). Hyperphosphatemia was more frequent in patients with moderate/severe CCC than in those with absent/mild CCC. We concluded that CCC was frequent in patients with CKD on dialysis and did not correlate with coronary calcium scores. Hyperphosphatemia appears to contribute to CCC. © 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

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Comparison of epitheliotrophic factors in autologous serum eyedrops from sera of chronic renal failure patients vs. normal controls

Kang

Lee

Jun

2015

Graefes Arch Clin Exp Ophthalmol

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Alterations in ocular surface and corneal thickness in relation to metabolic control in patients with chronic renal failure

Abstract: Dry eye and irritational symptoms are major ocular symptoms in CRF patients. Serum calcium and phosphate levels seem to have a prognostic importance for the ocular findings and symptoms in patients with CRF.

Cited by 43 publications

References 22 publications

Ocular Surface Findings in Chronic Renal Failure

Ocular Surface Findings in Chronic Renal Failure

Corneal and Coronary Calcification in Maintenance Hemodialysis: The Face Is No Index to the Heart

Comparison of epitheliotrophic factors in autologous serum eyedrops from sera of chronic renal failure patients vs. normal controls

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