Alteration of skin laser-Doppler flux response to local cooling in gestational hypertension

Cankar, Ksenija; Potočnik, Nejka; Štrucl, Martin

doi:10.1007/s10286-009-0050-1

Cited by 3 publications

(1 citation statement)

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“…[13] The cardiovascular reactivity adaptation seen in normal pregnancy is absent in gestational hypertension. [14] Thus it may be said that Doppler study for fetal surveillance in pregnancy-induced hypertension is a very useful device in reduction of perinatal morbidity and mortality by timely intervention. [15][16][17][18] Strengths of the study: The present study was conducted in a developing country with high incidence of maternal morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

A prospective study of doppler velocimetry in pregnancy-induced hypertension in a rural population of a developing country

Hazra¹,

Dash²,

Chaudhuri³

et al. 2013

J Basic Clin Reprod Sci

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Background: Pregnancy-induced hypertension (PIH) remains a great challenge to obstetricians. Doppler velocimetry can detect fetal compromise much before other antepartum tests. Aim: The aim of this study is to detect the changes of uterine artery, umbilical artery and middle cerebral artery in PIH by Doppler velocimetry. Subjects and Methods: This prospective study was conducted on hundred subjects with PIH. Doppler studies were carried, and parameters recorded in uterine, umbilical and middle cerebral artery (MCA) were Systolic/Diastolic ratio, Resistance Index, Cerebro-Placental Index (CPI). Fetal outcomes were monitored. Statistical analysis was performed using Epi Info TM software (Version 3.5.1, CDC, Atlanta). Test for significance was done with student's t-test and Chi-square where applicable. A P-value of<0.05 was considered as significant. Results: Among the 100 subjects, 76 (76%) of fetuses had abnormal and 24% normal umbilical artery Doppler velocimetry; 62% had abnormal and 38% normal MCA Doppler velocimetry; 64% fetuses had abnormal and 36% normal CPI. In 95% of subjects having abnormal umbilical Doppler studies, caesarean section had to be done for acute fetal distress. Incidence of caesarean section was 61% in abnormal MCA group and 63% in abnormal CPI group. Among 14 patients who had abnormal uterine artery Doppler, four developed pre-eclampsia, 2 IUGR. In patients with notches in uterine artery Doppler, 38% developed pre-eclampsia, 38% had IUGR, 13% babies were still born and 25% of newborns required NICU admission. In umbilical artery Doppler, when S/D ratio was abnormal, 60% developed pre-eclampsia, 40% had IUGR and 40% of newborns had to be admitted in NICU. Conclusion: Doppler study for fetal surveillance in pregnancy-induced hypertension is a very useful device and abnormal umbilical artery and uterine artery velocimetry seems to have worse pregnancy outcomes in the present study. Notch as a single parameter is the best indicator with highest sensitivity and positive predicative values. However, combination of parameters is the best indicator.

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Section: Discussionmentioning

confidence: 99%