Alteration of Glucidic Metabolism in Relation with Visceral Adiposity Index

Vladu, Ionela Mihaela; Radu, Lucreţiu; Girgavu, Sigina Rodica; Cojan, Tiberiu Ștefăniță Țenea; Ene, Cristina; Calborean, Veronica; Gheorman, Victor; Clenciu, Diana

doi:10.37358/rc.18.9.6558

Cited by 14 publications

(15 citation statements)

References 6 publications

(6 reference statements)

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“…Statistical analyses did not reveal any significance between the degree of positivity for the 2 markers (p=0.521). The degree of positivity for the 2 types of hormonal receptors (66% vs 58%) is similar to rate measured in all types of breast cancer no matter the type of surgical intervention and similar to the results observed in studies done of larger cohorts of patients [1][2][3][4] although variations may sometimes be more evident reported to the degree of positivity for the 2 receptors [5][6][7].…”

Section: Resultssupporting

confidence: 84%

Immunohistochemical analisys in Breast Carcinoma Treated with Conservative Surgery

Cojan¹,

Vladu²,

Clenciu³

et al. 2019

Rev. Chim.

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Breast cancer is the most common type of cancer in women worldwide and the second most common cancer overall, making it a major international concern from both socio and economical point of view. World Health Organisation (WHO) estimated that worldwide over 508.000 women died in 2011 due to breast cancer. American Cancer Society�s (ACS) study conducted in 2017 showed important numbers about the burden of breast cancer. Therefore, they estimated a number of 252,710 new breast cancer to be diagnosed in women and 2,470 in men in 2017- only in America. On 1st of January , there were about 3.5million US women with a history of breast cancer. The paper presents the correlations between recurrences of the tumor in breast cancer trated with conservative surgery and their immunohistochemical expression.

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Section: Resultssupporting

confidence: 84%

Immunohistochemical analisys in Breast Carcinoma Treated with Conservative Surgery

Cojan¹,

Vladu²,

Clenciu³

et al. 2019

Rev. Chim.

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“…In patients with HBV infection IL -6 serum levels are high and also IL -6 its prevents cell appoptosis . The serum levels of IL -6 are directly corelated with HBV progression and severity so drugs that block IL -6 is a theraphy strategy rather than monotherapy [36][37][38][39][40][41][42].…”

Section: Proinflammatory Cytokines In Chronic B-hepatitismentioning

confidence: 99%

Raspunsul gazdei la hepatita cronica virala B

Cringus¹,

Petrescu²,

Calborean³

et al. 2019

Rev. Chim.

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This review discusses and tries to demonstrate the importance of proinflammatory and antiinflammatory cytokines in HBV infection. Hepatitis B virus is a virus that is both hepatotropic and non-cytopathic. It causes the development of liver diseases which could progress into both acute and chronic versions. The virus is very widespread and results in the death of quite a number of people each year. The outcome of the viral infection is a result of immunologically mediated event. This means that the outcome is determined by the response of the immune system of the host. The infection can lead to several different liver diseases as well as fibrosis and cirrhosis. When an infection occurs, there is an attempt by the body to fight it via the use of several mechanisms. One of these is the use of cytokines (which are proteins). There exist different kinds of cytokines of which interleukin-10 and interferon gamma are very important. Interleukin-10 is an anti-inflammatory cytokine which inhibits the effector mechanism of Th1 cytokines. It performs hepatoprotective and anti-inflammatory functions and also upregulates Th2 cytokines. The function and relevance of this cytokine in the pathogenesis of liver diseases cannot be underemphasized. Interferon gamma, on the other hand, is a pro-inflammatory cytokine which seeks to eliminate and expunge the virus from the liver upon infection. It does this by congregating at the site of infection which subsequently results in inflammation and eventually liver fibrosis. This effect could be reversed by administering another type of interferon; interferon alpha.

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“…Older age and a long evolution of DM are factors known and shown in numerous studies to be associated with the development and progression of chronic complications in diabetes [27][28][29][30][31][32][33][34][35][36][37]…”

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confidence: 99%