1985
DOI: 10.1590/s0037-86821985000400002
|View full text |Cite
|
Sign up to set email alerts
|

Alterações quantitativas das células neuroendócrinas no Megacólon chagásico

Abstract: tilizando-se técnicas histoquím icas pela prata (M asson-F ontana e Sevier-M unger) estudaram -se a distribuição e o número de células enterocromafins (E C ) e do conjunto E C m ais células argirófilas (A R G ) em peças cirúrgicas de megassigmóide chagásico. Observou-se que tanto nos "m egas"(n = 16) com o nos controles (n -8), a posição das células E C e A R G na mucosa f o i predom inantemAs células endócrinas constituem importante componente da m ucosa digestiva e se distribuem desde as glândulas cárdicas a… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

0
2
0

Year Published

1991
1991
2001
2001

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(2 citation statements)
references
References 29 publications
0
2
0
Order By: Relevance
“…According to the concept of the enteroinsular axis (EIA), the PI should have important connections with the intestinal tube via the nervous, peptidergic, and substrate routes 37,38 . Increases in neuroendocrine system cell count 39 and gastrin serum levels [40][41][42] associated with reduction of pancreatic polypeptide (PP) levels have been reported 40,42 . Gastrin may act as a growth factor, performing direct trophic actions at various sites including the gastrointestinal mucus and the pancreas [43][44][45] .…”
Section: Discussionmentioning
confidence: 99%
“…According to the concept of the enteroinsular axis (EIA), the PI should have important connections with the intestinal tube via the nervous, peptidergic, and substrate routes 37,38 . Increases in neuroendocrine system cell count 39 and gastrin serum levels [40][41][42] associated with reduction of pancreatic polypeptide (PP) levels have been reported 40,42 . Gastrin may act as a growth factor, performing direct trophic actions at various sites including the gastrointestinal mucus and the pancreas [43][44][45] .…”
Section: Discussionmentioning
confidence: 99%
“…Parasite-induced disturbances in the activities of SP, VIP and of other types of neurotransmitters, such as enteroglucagon, somatostatin and acetylcholine (Polak et al, 1979;Long et al, 1980;Maifrino et al, 1998), may therefore be involved in the physio± pathogenic mechanism s operating in the megacolon of patients with Chagas disease (Barbosa et al,1985). Since SP and VIP have an antitrophic effect on the intestinal mucosa (Johnson, 1977), their decreased production may facilitate the action of substances with a trophic effect, inducing epithelial hyperplasia of the colon mucosa.…”
Section: Discussionmentioning
confidence: 99%