Alopecia with foreign body granulomas induced by Radiesse injection: A case report

Abstract

Radiesse is a soft tissue filler which has been widely used for cosmetic enhancement. The safety of Radiesse has been thoroughly investigated via numerous studies. A late-onset complication of Radiesse injection consists of foreign body granulomas, with only three case reports in over 10 years of clinical use. Herein, we describe the case of a patient who experienced alopecia with foreign body granulomas at the injection region one month after receiving a Radiesse injection. To our knowledge, this is the first report in the English literature of alopecia as an adverse event associated with Radiesse injection. The present case reminded physicians to evaluate more cautiously the necessity of injecting filler into hair-bearing area for lifting purpose. This procedure may cause foreign body granulomatous reaction, which may result in hair loss at the injection region.

Effective combination therapy with high concentration of Minoxidil and Carboxygas in resistant Androgenetic alopecia: Report of nine cases

“…Another case presented that it is important to evaluate more cautiously the necessity of injecting filler into the hair‐bearing area for lifting purpose. This procedure may cause foreign body granulomatous reaction, which may result in hair loss at the injection region 12. Our combination therapy method is based on the relationship between the administration of carboxygas and minoxidil (20%).…”

Detection of foreign objects in milk using an ultrasonic system

“…Ultrasonic has been successfully been applied for freezing, cavitation, emulsification and thermosonication for many types of food products [5][6][7]. Several investigationson foreign body detection using ultrasonic sensor had been carried out as reported by Correia et al [8], Zhao et al [9], Pallav et al [10],Leemans and Destain [11], Tantray et al [12] and Polat et al [13], Mcclements [14],Hassler and Homayoon [15], Le Coz et al [16],Iuliano [17], Liu et al [18], Liaw et al [19], Makinde et al [20], Holmes et al [21], Melo et al [22], Khan et al [23], Prabhakar et al [24],Rodrigues et al [25], Franchini et al [26], Pandey [27], Aftab et al [28], Gounder and Tan [29], Sadaka et al [30], Fasina et al [31], Khan et al [32], Mitev et al [33], Roux et al [34], Nakib et al [35], Rathore [36], Singleton et al [37], Mahesh et al [38], Ezenwa [39], Natung [40] and Mustapha [41], In this paper, two common foreign bodies materials e.g. steel and rubber with different sizes were used to investigate the sensor voltage and voltage loss at the ultrasonic receiver.…”

Filler‐induced alopecia

“…In frontal FIA, the proposed mechanism was granulomatous foreign body reaction with destruction of the hair follicle. 4 However, considering the hair regrowth after 6 months, the proposed mechanism could be incorrect, and the possibility of vascular compromise due to filler is considered to be more likely. The onset of FIA after filler injection was 1 week (our case), 2 weeks (two cases) and 4 weeks (one case).…”

“…Since the first report of FIA by Gan et al in 2013, 2 there have only been three cases to date. [2][3][4] All cases were of women. Two of these cases were ipsilateral on the temporal scalp after HA filler injection, and one case was on the forehead after calcium hydroxyapatite filler.…”

“…These mutations were classified as "likely pathogenic" according to the guidelines of the American College of Medical Genetics. 4 It was suggested that the mutations on the N and C terminals of LSS may result in hypotrichosis and congenital cataract, respectively. 3 However, the patients in our family who harbored…”