Quinones have been of particular enthusiasm to established researchers because of their enormous applicable properties. Synthesized and natural anthraquinone based derivatives are now era of concern for researchers due to their distinctive properties. Intensive research has been made with special focus on laxative, antiulcerogenic, inhibition of enzymes, cytotoxicity, antimicrobial, anti-inflammatory, antiarthritic, antirheumatic, antidepressant, fungicidal, insecticidal, antioxidant and antitumor activity of anthraquinone based derivatives. With the awareness of environment protection need, safe and healthy, free of pollution, disease and particularly to maintain green, these derivatives are being used, acknowledged in medicinal research as well as in pharmaceutical world. Anthraquinone linked with amino derivatives have wide-spectrum therapeutic applications and being a center of focus as important biological scaffold in different fields like medicines, electronic industry, cosmetics. Owing to the remarkable activities of anthraquinone we outline the structural data, their sources, synthetic routes and therapeutic potentials.