Allium Chemistry: Identification of Natural Abundance Organoselenium Compounds in Human Breath after Ingestion of Garlic Using Gas Chromatography with Atomic Emission Detection

Preparation of Selenium-enriched Sprouts and Identification of Their Selenium Species by High-performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry

“…These monomethylated selenoamino acids have been identified in several selenium-enriched vegetables. [6][7][8] The anticancer activities of these highselenium vegetables have also been evaluated [9][10][11] and found to be higher than that of selenite. 12,13) Thus, the application of high-selenium vegetables to cancer prevention can be expected.…”

Analytical selenoamino acid studies by chromatography with interfaced atomic mass spectrometry and atomic emission spectral detection

“…Even in such selenium-rich plants as garlic (Allium, sativum) high levels of analogous sulfur species are present and element selective detection is valuable in differentiating species by element content. Thus 'selenium breath' following ingestion of garlic has been successfully monitored [17]. GC of selenoamino acids has been carried out by derivatization to volatile species using ethyl chloroformate followed by element selective GC-AED [18].…”

Selective detection and identification of Se containing compounds—review and recent developments

“…Headspace-GC-AED was used to detect selenium compounds in members of the Allium family such as garlic, elephant garlic, onion and broccoli (Brassica) [60]. Natural abundance organoselenium compounds in human breath after ingestion of garlic were identified using Tenax trap/cryogenic-GC-AED [61]. Calle-Guntinas et al [62] reported absolute detection limits of 10 pg for dimethylselenide.…”

“…Many epidemiological studies have pointed to an inverse association of Se status and risk to at least some cancers [17,61]. Most animal studies have shown that supranutritional levels of various Se-compounds can reduce the yields of tumors caused by chemical or viral carcinogens [17][18][19][20].…”