Allergy to lidocaine injections: comparison of patient history with skin testing in five patients

Jenerowicz, Dorota; Polańska, Adriana; Glińska, Olga; Czarnecka‐Operacz, Magdalena; Schwartz, Robert A.

doi:10.5114/pdia.2014.40937

Cited by 25 publications

(22 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dostupni podaci ukazuju da se skoro na svaki amidni lokalni anestetik u praksi pojavljuje alergijska reakcija, sa određenom rastućom stopom [29][30][31][32][33][34][35][36] . U slučaju sumnje na alergiju na lokalne anestetičke rastvore, preporučuje se primena čistog lokalnog anestetika, bez prisustva stabilizatora koji je mogući antigen, ili upotreba drugog anestetika.…”

Section: Allergic Reactions To Local Anestheticsunclassified

“…Available data indicate that almost every amide local anesthetic in practice causes allergic reaction, with a specific growing pace [29][30][31][32][33][34][35][36] . In the case of suspected allergy to the local anesthetic solutions use of pure local anesthetic is recommended, without the presence of a stabilizer which is a potential antigen, or use of a different anesthetic.…”

Section: Allergic Reactions To Local Anestheticsmentioning

confidence: 99%

See 1 more Smart Citation

Systemic adverse reactions to local anesthetics

Tijanić¹,

Stojanović²,

Burić³

et al. 2019

Acta stomatologica Naissi

View full text Add to dashboard Cite

Uvod:Lokalni anestetici su najčešće korišćeni lekovi u svakodnevnoj stomatološkoj i medicinskoj, a sve češće i u kozmetičkoj praksi. Danas postoji veliki broj lokalnih anestetika koji su prema strukturi podeljeni na dve grupe: estarske i amidne lokalne anestetike. Iako je njihova primena u svakodnevnom radu uglavnom bezbedna, nije isključena mogućnost pojave negativnih reakcija koje mogu biti psihogene, toksične, imunološke i specifične neželjene reakcije. Cilj: ovog rada je da ukaže na mehanizam nastanka i simptomatologiju mogućih negativnih reakcija na lokalne anestetike. Zaključak:Ukoliko dođe do pojave sistemske neželjene reakcije na lokalni anestetik, najveći problem, u kliničkoj praksi, predstavlja prepoznavanje prirode negativne reakcije i pružanje adekvatne terapije u vezi sa nastalom reakcijom.Brzina i sigurnost u prepoznavanju neželjene reakcije na lokalni anestetik, nekada mogu biti od životnog značaja za bolesnika. AbstractIntroduction: Local anesthetics are the most commonly used drugs in everyday dental and medical and increasingly in cosmetic practice. Today there are a number of local anesthetics that are divided into two groups based on their structure: ester and amide local anesthetics. Although their use in everyday work is generally safe, there is a possibility of adverse reactions that may be psychogenic, toxic, immunologic and specific adverse reactions. The aim of this work is to highlight the mechanism of occurrence and symptoms of possible adverse reactions to local anesthetics. Conclusion: If you experience systemic adverse reactions to the local anesthetic, the biggest problem in clinical practice, is a recognition of the nature of adverse reactions and providing appropriate therapy in conjunction with the resulting reaction. Speed and security to identify adverse reactions to local anesthetic can be of vital importance for the patient.

show abstract

Section: Allergic Reactions To Local Anestheticsunclassified

Section: Allergic Reactions To Local Anestheticsmentioning

confidence: 99%

Systemic adverse reactions to local anesthetics

Tijanić¹,

Stojanović²,

Burić³

et al. 2019

Acta stomatologica Naissi

View full text Add to dashboard Cite

show abstract

“…In cases where a true allergy to the local anaesthetic agent is present, it is most commonly a reaction to the common metabolic product of ester local anaesthetics called para‐amino benzoic acid. As this is a common metabolite, cross‐reactivity between different esters occurs and an allergy to one ester eliminates the possibility of the use of another . Allergic reactions to amide dental local anaesthetics are exceedingly rare and, in contrast to esters, an allergy to one amide does not necessarily rule out the use of another (Table )…”

Section: Introductionmentioning

confidence: 99%

“…Once an adverse reaction occurs in the dental office, it is important that its cause is thoroughly examined. Although a true allergy to local anaesthetic is rare, thorough investigation and accurate diagnosis can protect the patient from a future severe, potentially life‐threatening event . On the other hand, investigation may also allow for the identification of allergy to preservatives, latex or a physiological/psychogenic manifestation that might have led to the observed reaction .…”

Section: Introductionmentioning

confidence: 99%

Investigation and diagnosis of an immediate allergy to amide local anaesthetic in a paediatric dental patient

Allen

Chan

Gue

2017

Australian Dental Journal

View full text Add to dashboard Cite

Local anaesthetics remain the most common prescription medication utilized in dental practise. Adverse reactions following administration of local anaesthetic are somewhat common and are frequently reported as 'allergies'. However, of these events, it is estimated that only 1% are confirmed allergies to the local anaesthetic. This case report presents the process of referral for investigation and testing to confirm an amide local anaesthetic allergy in a paediatric patient. Testing for a safe alternative was also completed to identify local anaesthetic agents also of the amide variety that could be utilized safely on this individual. Following skin testing of alternative agents, intraoral challenges were completed. Finally, restorative dental treatment was provided safely for the patient with the use of an alternative amide local anaesthetic on a number of occasions with no further adverse outcomes.

show abstract

“…Lidocaine toxicity and anaphylaxis is rare but unfortunately lethal insult is sometimes reported in outpatient clinics. 4 Although use of epinephrine especially in cardiovascular patients can suddenly raises the blood pressure and heart rate, 6,7 but some studies have shown that the amount of epinephrine that is usually added to lidocaine as a local anesthesia is safe and has no considerable effect on the cardiac parameters. 8 However, epinephrine dosage should be minimized, for patients with significant cardiovascular disease, in particular ischemic heart disease.…”

mentioning

confidence: 99%