Allergy to latex, avocado pear, and banana: Evidence for a 30 kd antigen in immunoblotting

Lavaud, F.; Prévost, Alain; Cossart, C.; Guérin, Laurence; Bernard, J.; Kochman, S

doi:10.1016/s0091-6749(95)70318-7

Cited by 134 publications

(50 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…First, there could be a cross-reaction between latex and mountain cedar in which similar or identical proteins are found in both allergen sources. Cross-reactivity has already been demonstrated between latex and banana, kiwi, chestnut, avocado, and peanut (29,30). Our results using IgG from rabbits specifically immunized with latex glove extract showed the presence of cross-reactive material in mountain cedar extracts in the Western blots.…”

Section: Resultssupporting

confidence: 72%

“…By using Western blot analyses to identify human IgE bound to electrophoresis proteins, well over 50 allergenic bands have been reported, with major bands occurring in the 14 and 30 kDa regions (39). Recent studies have shown that the sera of several food-sensitive and latex-sensitive patients recognize a 30 kDa allergen (30). Furthermore, a 36 kDa allergen, frequently encountered by sera of patients with latex allergy (40), has been purified and shows homology to plant endo 1,3-0-glucosidases (41).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Latex allergens in tire dust and airborne particles.

Miguel

Cass

Weiss

et al. 1996

Environ Health Perspect

View full text Add to dashboard Cite

show abstract

Section: Resultssupporting

confidence: 72%

Section: Resultsmentioning

confidence: 99%

Latex allergens in tire dust and airborne particles.

Miguel

Cass

Weiss

et al. 1996

Environ Health Perspect

View full text Add to dashboard Cite

show abstract

“…Several reports indicate that NRL allergens may crossreact with latex from the weeping fig (Ficus benjamina) [39], and various fruits (banana, avocado, passion fruit, kiwi and chestnut) [40][41][42][43][44]. A recent study suggests that NRL and fruits have common epitopes on 30 kDa proteins [45].…”

Section: Nrl Allergensmentioning

confidence: 99%

Occupational asthma caused by natural rubber latex

Vandenplas¹

1995

Eur Respir J

View full text Add to dashboard Cite

O Oc cc cu up pa at ti io on na al l a as st th hm ma a c ca au us se ed d b by y n na at tu ur ra al l r ru ub bb be er r l la at te ex x Recent studies indicate that asthma is a frequent manifestation of NRL allergy among workers manufacturing NRL materials and among health-care providers using NRL gloves. NRL-induced asthma should receive increasing attention as it can lead to permanent respiratory sequelae and occupational disability. The need for early and accurate diagnosis is outlined and the different diagnostic approaches are reviewed. Specific issues pertaining to the management of affected subjects and to the prevention of exposure to airborne NRL are discussed.Areas of future research should include: 1) further characterization of relevant NRL allergens; 2) development and validation of methods for quantitative assessment of allergen content in NRL devices and workplace environments; 3) standardization of allergen extracts used for diagnostic purposes; 4) prospective evaluation of the natural history and risk factors of NRL-induced asthma; and 5) analysis of effectiveness and cost of preventive strategies.

show abstract

“…It is a lectin that belongs to the defense related family of proteins [10,11]. This polypeptide chain is present as a chitin-binding domain in several plant proteins, such as multi-hevein domain lectins and class I chitinases [12,13], which have been associated with cross-reactivity between latex and some fruits [14,15]. Recently, information regarding conformational epitopes of this allergen has been described: Karisola et al [16,17], using, chimeric-hevein, hevein mutants and molecular modeling suggested that the N-terminal and C-terminal regions essentially determined the IgE binding activity.…”

Section: Introductionmentioning

confidence: 99%

A single amino acid substitution on the surface of a natural hevein isoform (Hev b 6.0202), confers different IgE recognition

et al. 2006

View full text Add to dashboard Cite

Decreased immune reactivity of isoforms of major allergens has been reported. However, such claims have always been based on experiments with recombinant proteins. This work describes the molecular and physicochemical characterization of a hevein (Hev b 6.0201) natural isoform (Hev b 6.0202), which is present in rubber latex from Hevea brasiliensis. The isoallergen has a single substitution Asn14Asp, which gives rise to local differences in the surface potential, as observed from the crystal structure presented here. Besides, ELISA inhibition using serum pools of adult and pediatric patients showed reduced IgE-binding capacity ($27%) with the isoallergen. Overall, these results are relevant to delineate crucial residues involved in this dominant discontinuous epitope.

show abstract

Allergy to latex, avocado pear, and banana: Evidence for a 30 kd antigen in immunoblotting

Cited by 134 publications

References 21 publications

Latex allergens in tire dust and airborne particles.

Latex allergens in tire dust and airborne particles.

Occupational asthma caused by natural rubber latex

A single amino acid substitution on the surface of a natural hevein isoform (Hev b 6.0202), confers different IgE recognition

Contact Info

Product

Resources

About