Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies

Calderón, Moisés A.; Demoly, Pascal; Casale, Thomas B.; Akdiş, Cezmi A.; Bachert, Claus; Bewick, Mike; Bilò, Beatrice M; Bohle, Barbara; Бонини, С.; Bush, Andy; Caimmi, Davide; Canonica, Giorgio Walter; Cardona, Victòria; Chiriac, Anca‐Mirela; Cox, L.; Čustović, Adnan; Blay, F. De; Devillier, P.; Didier, A.; Lorenzo, Gabriele Di; Toit, George Du; Durham, Stephen R.; Eng, P. A.; Fiocchi, Alessandro; Fox, Adam; Wijk, Roy Gerth van; Gómez, René Maximiliano; Haathela, T.; Halken, Susanne; Hellings, Peter W.; Jacobsen, Lars; Just, Jocelyne; Tanno, Luciana Kase; Kleine‐Tebbe, Jörg; Klimek, Ludger; Knol, Edward F.; Kuna, Piotr; Larenas‐Linnemann, Désirée; Linneberg, Allan; Matricardi, M.; Malling, Hans‐Jørgen; Moesges, R.; Mullol, Joaquim; Muraro, Antonella; Papadopoulos, Nikolaos G.; Passalacqua, G.; Pastorello, Elide A.; Pfaar, Oliver; Price, David; Río, Pablo Rodríguez del; Rueff, R.; Samoliński, Bolesław; Scadding, Glenis K.; Senti, Gabriela; Shamji, Mohamed H.; Sheikh, Aziz; Sisul, Juan‐Carlos; Solé, Dírceu; Sturm, Gunter J.; Tabar, A. I.; Ree, Ronald van; Ventura, M. T.; Vidal, Carmen; Varga, Eva‐Maria; Worm, Margitta; Zuberbier, Torsten; Bousquet, Jean

doi:10.1186/s13601-016-0131-x

Cited by 24 publications

(5 citation statements)

References 125 publications

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“…On the other hand, The American Academy of Allergy, Asthma and Immunology (AAAAI) has concluded that such an AIT might be effective. An international consensus on immunotherapy indicated the possibility of AIT for mold allergy, but only with standardized extracts [ 93 ].…”

Section: Immunotherapy For Alternaria Sensitizationmentioning

confidence: 99%

Alternaria as an Inducer of Allergic Sensitization

Hernández-Ramírez

Barber

Tomé-Amat

et al. 2021

JoF

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Alternaria alternata is a saprophytic mold whose spores are disseminated in warm dry air, the typical weather of the Mediterranean climate region (from 30° to 45°), with a peak during the late summer and early autumn. Alternaria spores are known to be biological contaminants and a potent source of aeroallergens. One consequence of human exposure to Alternaria is an increased risk of developing asthma, with Alt a 1 as its main elicitor and a marker of primary sensitization. Although the action mechanism needs further investigation, a key role of the epithelium in cytokine production, TLR-activated alveolar macrophages and innate lymphoid cells in the adaptive response was demonstrated. Furthermore, sensitization to A. alternata seems to be a trigger for the development of co-sensitization to other allergen sources and may act as an exacerbator of symptoms and an elicitor of food allergies. The prevalence of A. alternata allergy is increasing and has led to expanding research on the role of this fungal species in the induction of IgE-mediated respiratory diseases. Indeed, recent research has allowed new perspectives to be considered in the assessment of exposure and diagnosis of fungi-induced allergies, although more studies are needed for the standardization of immunotherapy formulations.

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Section: Immunotherapy For Alternaria Sensitizationmentioning

confidence: 99%

Alternaria as an Inducer of Allergic Sensitization

Hernández-Ramírez

Barber

Tomé-Amat

et al. 2021

JoF

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“…Similarly, Calderon el al. ( 761 ) have launched a study to identify the effects, reliability, cost-benefit analysis and comorbidities of allergen immunotherapy in the elderly for a healthy and active aging.…”

Section: Special Conditions In Treatment Of Allergic Rhinitismentioning

confidence: 99%

Turkish Guidelines for Diagnosis and Treatment of Allergic Rhinitis (ART)

Ecevit¹,

Özcan²,

Can³

et al. 2021

TAO

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Object: To prepare a national guideline for Otorhinolaryngologist who treat allergic rhinitis patients. Methods: The study was conducted by three authors, namely the writing support team. The support team made the study plan, determined the writing instructions, chose the subgroups including the advisory committee, the advisors for authors and the authors. A workshop was organized at the very beginning to explain the details of the study to the team. Advisors took the chance to meet their coworkers in their subgroups and determined the main headings and subheadings of the guideline, together with the authors. After key words were determined by the authors, literature search was done in various databases. The authors keep in touch with the advisors and the advisors with the advisory committee and the support group at every stage of the study. National and International published articles as well as the abstracts of unpublished studies, imperatively presented in National Congresses, were included in this guideline. Only Guideline and meta-analyses published in last seven years (2013-2017) and randomized controlled studies published in last two years (2015-2017) were included. After all work was completed by the subgroups, support team brought all work together and edited the article. Results: A detailed guideline about all aspects of allergic rhinitis was created. Conclusion: The authors believe that this guideline will enable a compact and up-to-date information on allergic rhinitis to healthcare professionals. This guideline is the first in the field of Otolaryngology in Turkey. It should be updated at regular intervals.

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“…The vast majority of patients who visit GPs or specialists have moderate/severe rhinitis [ 85 – 87 ]. A large number of OTC or prescribed drugs are available for the patient who can also choose alternative medicine or allergen-specific immunotherapy [ 88 ]. The app will also be useful in the early identification of those who are unaware of being affected by allergic rhinitis, and of the fact that symptoms can be controlled.…”

Section: Chrodis Check Listmentioning

confidence: 99%

CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report

Bousquet

Onorato²,

Bachert

et al. 2017

Clin Transl Allergy

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A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.

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Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies

Cited by 24 publications

References 125 publications

Alternaria as an Inducer of Allergic Sensitization

Alternaria as an Inducer of Allergic Sensitization

Turkish Guidelines for Diagnosis and Treatment of Allergic Rhinitis (ART)

CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report

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