CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report

Background Allergies to cats are the most common animal‐origin allergy, and affect approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals has been increasing, and allergy to cats is a major risk factor for the development of asthma and rhinitis. The diagnosis of cat allergy is now well established. The exact significance of component‐resolved diagnosis in the diagnosis of cat allergy remains to be fully understood. Allergen avoidance is effective but often has a psychologic impact. Allergen immunotherapy is not well demonstrated. There is a need for innovative approaches to better manage cat allergens. Next‐generation care pathways for asthma and rhinitis will define the place of cat allergen avoidance. Methods and Results This manuscript, based on content presented at the European Academy of Allergy and Clinical Immunology Congress 2019, provides information on the prevalence and impact of cat allergies and the molecular biology of Fel d 1, the major cat allergen. Discussion The authors present the scientific basis of a novel care pathway that utilizes anti‐Fel d 1 IgY antibodies to safely and effectively neutralize Fel d 1 after its production by the cat but before human exposure. Conclusion Efficacy of a feline diet with an egg product ingredient containing anti‐Fel d 1 IgY antibodies was demonstrated in vitro, ex vivo, and in vivo, and further validated by a pilot exposure study involving cat‐allergic human participants.

Section: Next‐generation Care Pathways Of Cat Allergymentioning

confidence: 99%

Keep the cat, change the care pathway: A transformational approach to managing Fel d 1, the major cat allergen

Satyaraj¹,

Wedner

Bousquet

2019

“…The results of the current study will be used in the development of the MASK sentinel network and predictive medicine . MASK (Mobile Airways Sentinel network) uses mobile technology to develop care pathways for the management of rhinitis and asthma by a multidisciplinary group and by patients themselves . The scaling up strategy uses the recommendations of the European Innovation Partnership on Active and Healthy Ageing …”

Section: Discussionmentioning

confidence: 99%

Google Trends and pollen concentrations in allergy and airway diseases in France

Bousquet

Onorato²,

Oliver

et al. 2019

Background: Google Trends (GTs) is a web-based surveillance tool that explores the searching trends of specific queries via Google. This tool proposes to reflect the real-life epidemiology of allergic rhinitis and asthma. However, the validation of GTs against pollen concentrations is missing at the country level.Objectives: In the present study, we used GTs (a) to compare the terms related to allergy in France, (b) to assess seasonal variations across the country for 5 years and (c) to compare GTs and pollen concentrations for 2016.Methods: Google Trends queries were initially searched to investigate the terms reflecting pollen and allergic diseases. 13-and 5-year GTs were used in France. Then, 5-year GTs were assessed in all metropolitan French regions to assess the seasonality of GTs. Finally, GTs were compared with pollen concentrations (Réseau National de Surveillance en Aerobiology) for 2016 in seven regions (GTs) and corresponding cities (pollen concentrations). Results:The combination of searches for "allergy" as a disease, "pollen" as a disease cause and "ragweed" as a plant was needed to fully assess the pollen season in France. "Asthma" did not show any seasonality. Using the 5-year GTs, an annual and clear seasonality of queries was found in all regions depending on the predicted pollen exposure for spring and a summer peak but not for winter peaks. The agreement between GT queries and pollen concentrations is usually poor except for spring trees and grasses. Moreover, cypress pollens are insufficiently reported by GTs. Conclusions:Google Trends cannot predict the pollen season in France. K E Y W O R D Sallergy, asthma, google trends, pollen, rhinitis G R A P H I C A L A B S T R A C TGoogle Trends (GTs) is a web-based tool that explores searching trends. This tool was used to search the terms related to allergy in France, to assess 5-year seasonal variations across the country and to compare GTs with the pollen concentrations for 2016. The combination of terms "allergy," "pollen" and "ragweed" was needed to fully assess the pollen season in France. GTs cannot predict the pollen season in France.

“…The Allergy Diary (MASK‐rhinitis) has been implemented in 23 countries and 16 languages. Over 23 000 users have been recorded . This tool appears to be appropriate for pharmacists, in particular since it is extremely simple, does not require the pharmacist to undertake any particular education on its use, is user‐friendly for the patient, and can be used for follow‐up over time.…”

Section: Management Of Allergic Rhinitis In the Pharmacy: Aria‐pharmamentioning

confidence: 99%

ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”

Bosnic‐Anticevich

Costa

Menditto

et al. 2019

Pharmacists are trusted health care professionals. Many patients use over‐the‐counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)‐pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA‐pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care.