Allergic rhinitis in children with attention-deficit/hyperactivity disorder

Brawley, Ashley; Silverman, Bernard A.; Kearney, Shannon; Guanzon, Denise; Owens, Mark; Bennett, Harvey; Schneider, Arlene T.

doi:10.1016/s1081-1206(10)61434-2

Cited by 77 publications

(65 citation statements)

References 22 publications

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“…As we have seen, allergic disorders can lead to significant cognitive distortions, especially during the peak allergy season (e.g., ragweed season); interestingly, this effect was found only in a subgroup of patients [8]. These disorders have also been associated with such conditions as depression, anxiety, and panic disorder, thus raising the question as to whether these shared maladies are the result of shared genetic risks or some common mechanism, which may exist between allergic disorders and mental diseases [42].…”

Section: Discussionmentioning

confidence: 81%

“…While the etiology of ADHD is unknown, it is most likely the result of interplay between various neuroanatomical/neurochemical systems and genetic and psychological factors [6]. An association between ADHD and allergy has long been touted but remains controversial [7][8][9][10]. It has also been suggested that children with ADHD and those with allergic disease may share a common biological background [7,11,12].…”

Section: Introductionmentioning

confidence: 99%

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Attention Deficit Disorder and Allergic Rhinitis - Are They Related?

Melamed¹

2016

Int J Aller Medcations

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The association between ADHD and allergy remains controversial. Our previous findings suggest that nerve growth factor may link the nervous and immune systems. The primary objective of this study was to determine if a combination of cetirizine + methylphenidate is effective in children with comorbid ADHD and allergic rhinitis. We also examined the role of nerve growth factor in these comorbidities. Our randomized, double-blind, placebo-controlled, crossover study enrolled 38 children diagnosed with comorbid ADHD and allergy using cetirizine ( = 12), sustained-release methylphenidate ( = 12), or cetirizine + methylphenidate ( = 14). Endpoints compared baseline to posttreatment evaluations for allergic rhinitis and ADHD scores. Serum nerve growth factor levels were measured using ELISA. For allergy endpoints, combination therapy produced results superior to individual therapy. For ADHD, similar scores were achieved for individual therapy; however, combination therapy resulted in improved scores. Nerve growth factor levels were downregulated following this trend. We conclude that ADHD and allergic rhinitis may have common mechanism and represent a comorbid condition that links the nervous system to the immune system. Further studies are needed.

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Section: Discussionmentioning

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Attention Deficit Disorder and Allergic Rhinitis - Are They Related?

Melamed¹

2016

Int J Aller Medcations

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“…Yorgunluk ve halsizlik çok yaygın olarak izlenir, ancak hastalar nadiren bu semptomları doğrudan bildirir (19). Allerjik rinit, dikkat eksikliği hiperaktivite bozukluğu, pik polen mevsiminde daha düşük sınav puanları, düşük konsantrasyon, bozulmuş atletik performans ve düşük benlik saygısı gibi, çocuklar ve ergenlerde bir dizi bilişsel ve psikiyatrik sorunlarla ilişkilidir (20,21).…”

Section: Klinik Belirti Ve Bulgularunclassified

Allerjik Rinit

Şimşek¹,

Yılmaz²,

Yüksel³

2018

Asthma Allergy Immunol

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“…Therefore, assessment of allergic sensitization may be beneficial in children diagnosed with ADHD [21]. And evaluation and treatment of AR could benefit patients with ADHD [22]. As a result, besides allergists psychiatrists should be more aware of the co-morbidity of AR when treating ADHD patients.…”

Section: Attention Deficit Hyperactivity Disorder (Adhd)mentioning

confidence: 99%

Correlation Between Prevalence of Allergic Rhinitis and Certain Diseases

Özdemir¹

2015

MOJI

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Allergic rhinitis is the most common chronic inflammatory disease of the upper respiratory tract, and its symptoms include watery rhinorrhea, sneezing, itching and nasal congestion. There have been quite different results for the prevalence of allergic diseases in different parts of world detected by surveys. However more amazingly, the international patterns of allergic disease prevalence cannot be explained by the current perception of the etiology of these conditions. Differences have been usually thought to be due to genetics, hygiene, diet, and environmental factors and not to be related to simply increased awareness of the disease. When current literature searched in detail, some of well-known specific diseases seem to be risk factors affecting development of allergic rhinitis. In this mini review, our aim is try to explain whether any relation between increasing allergic rhinitis prevalence and some specific disorders under the light of recent literature.

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Allergic rhinitis in children with attention-deficit/hyperactivity disorder

Cited by 77 publications

References 22 publications

Attention Deficit Disorder and Allergic Rhinitis - Are They Related?

Attention Deficit Disorder and Allergic Rhinitis - Are They Related?

Allerjik Rinit

Correlation Between Prevalence of Allergic Rhinitis and Certain Diseases

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