Allergic effects of the residual monomer used in denture base acrylic resins

Rashid, Haroon; Sheikh, Zeeshan; Vohra, Fahim

doi:10.4103/1305-7456.172621

Cited by 81 publications

(79 citation statements)

References 54 publications

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“…The released monomer is suspected of being responsible for allergic or chemical-irritative (cytotoxic) reactions to denture base materials [11, 12]. The resulting symptoms reportedly range from burning oral sensations [13], stomatitis [14] to edema and even ulceration of the oral mucosa [15].…”

Section: Introductionmentioning

confidence: 99%

Do CAD/CAM dentures really release less monomer than conventional dentures?

et al. 2016

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ObjectivesComputer-aided design (CAD)/computer-aided manufacturing (CAM) dentures are assumed to have more favourable material properties than conventionally fabricated dentures, among them a lower methacrylate monomer release. The aim of this study was to test this hypothesis.Materials and methodsCAD/CAM dentures were generated from ten different master casts by using four different CAD/CAM systems. Conventional, heat-polymerised dentures served as control group. Denture weight and volume were measured; the density was calculated, and the denture surface area was assessed digitally. The monomer release after 7 days of water storage was measured by high-performance liquid chromatography.ResultsWhole You Nexteeth and Wieland Digital Dentures had significantly lower mean volume and weight than conventional dentures. Baltic Denture System and Whole You Nexteeth had a significantly increased density. Baltic Denture System had a significantly smaller surface area. None of the CAD/CAM dentures released significantly less monomer than the control group.ConclusionsAll tested dentures released very low amounts of methacrylate monomer, but not significantly less than conventional dentures. A statistically significant difference might nevertheless exist in comparison to other, less recommendable denture base materials, such as the frequently used autopolymerising resins.Clinical relevanceCAD/CAM denture fabrication has numerous advantages. It enables the fabrication of dentures with lower resin volume and lower denture weight. Both could increase the patient comfort. Dentures with higher density might exhibit more favourable mechanical properties. The hypothesis that CAD/CAM dentures release less monomer than conventional dentures could, however, not be verified.

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Section: Introductionmentioning

confidence: 99%

Do CAD/CAM dentures really release less monomer than conventional dentures?

et al. 2016

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“…It consists of an acrylic denture base with acrylic resin teeth. Allergic reactions to denture bases have been reported due to leaching of monomer in self cure resin appliances (Rashid et al, 2015). Toxic substances leached from the resins can have cytotoxic effects and cause irritability in the mucosa (Mac Cabe and Basker, 1976).…”

Section: Discussionmentioning

confidence: 99%

Management of dental trauma in a child with Xeroderma Pigmentosa

Agarwal¹,

Kumar²,

Sharma³

et al. 2018

The Saudi Dental Journal

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Xeroderma Pigmentosa is a rare dermatological autosomal recessive disorder that manifests itself early in life as severe sunburn usually after a short exposure to sunlight. The prime characteristic features include photosensitivity, hyperpigmentation and ichthyosis in sun exposed areas, and an increase in the risk of basocellular and squamous cell carcinomas and melanomas of the skin and eyes. The case report highlights the preventive treatment options along with all necessary precautions that should be taken to protect the patient from any iatrogenic inadvertent exposures that may be deleterious to his present state. The purpose of the report is also to discuss the important role of dental professionals when dealing with debilitating medical conditions.

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“…However, some authors have reported allergic reactions to an unbound monomer of acrylic materials [22, 29, 30]. …”

Section: Discussionmentioning

confidence: 99%

Determination of Salivary Myeloperoxidase, Immunoglobulin E, and Tumor Necrosis Factor-α after Complete Denture Insertion

et al. 2019

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Objective: To detect activities of salivary myeloperoxidase (MPO) and concentrations of salivary tumor necrosis factor (TNF)-α as indicators of inflammatory reaction and salivary immunoglobulin E as an indicator of allergic reaction after complete insertion of acrylic dentures. Subjects and Methods: Complete dentures were made for a uniform group of elderly patients, and saliva samples were taken immediately before they were given to the patients, as well as 2, 3, 7, and 30 days after insertion of the dentures, with simultaneous monitoring of changes in the oral mucosa. Results: After 7 and 30 days of wearing upper and lower complete dentures, nonsignificant increases in salivary MPO and TNF-α were proven to be indicators of inflammation. No changes were observed in the values of salivary immunoglobulin E during a 30-day observational period, which excluded the appearance of allergic reactions to acrylic materials in the tested group of patients. Conclusion: A nonsignificant increase in the levels of MPO was observed on day 7; it decreased after 30 days. TNF-α also tended to increase in a nonsignificant manner.

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Allergic effects of the residual monomer used in denture base acrylic resins

Cited by 81 publications

References 54 publications

Do CAD/CAM dentures really release less monomer than conventional dentures?

Do CAD/CAM dentures really release less monomer than conventional dentures?

Management of dental trauma in a child with Xeroderma Pigmentosa

Determination of Salivary Myeloperoxidase, Immunoglobulin E, and Tumor Necrosis Factor-α after Complete Denture Insertion

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