Allele frequency data for 17 short tandem repeats in a Czech population sample

Šimková, Halina; Faltus, Václav; Marvan, Richard; Pexa, Tomáš; Stenzl, Vlastimil; Brouček, Jaroslav; Hořínek, Aleš; Mazura, I; Zvárová, Jana

doi:10.1016/j.fsigen.2009.01.003

Cited by 12 publications

(2 citation statements)

References 18 publications

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“…Nowadays more than 94% of people living in the Czech Republic declare themselves as Czechs, thereby creating an overwhelming majority . Several population studies involving autosomal STRs , Y‐STRs , insertion‐deletion polymorphisms , and unlinked X‐STRs were performed on Czech population.…”

Section: Introductionmentioning

confidence: 99%

Investigator® Argus X‐12 study on the population of Czech Republic: Comparison of linked and unlinked X‐STRs for kinship analysis

et al. 2014

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DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator® Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator® Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator® Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kits. Investigator® Argus X-12 proved to be very useful for sibship determination, since its LR values were relatively similar to LR for autosomal STR kit. This work presents the first population data for Investigator® Argus X-12 system in the Czech Republic.

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Section: Introductionmentioning

confidence: 99%

Investigator® Argus X‐12 study on the population of Czech Republic: Comparison of linked and unlinked X‐STRs for kinship analysis

et al. 2014

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“…At locus D19S433, four peaks are displayed. Table 1 shows peak heights and allele frequencies in Czech population [10]. There are two suspects with alleles 14, 15 and 15, 16.…”

Section: Probability Of Dropoutmentioning

confidence: 99%

Stochastic Models for Low Level DNA Mixtures

Slovák¹,

Zvárová²

2012

ejbi

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Objectives: The increasing sensitivity of forensic analysis methods allows to investigate less and less amount of biological samples. For samples of low quality or quantity, there are stochastic events that require intensive statistical analysis.Methods: There are several models how to calculate the probability of a given set of alleles. We have described three of them and compared them to verify their accuracy. Results: The two models proposed in [1] extend so far the most widely used model by the possibility of dropout and peak areas of individual alleles.The first one is incorrect, while the second model highly improves the possibility of DNA mixture analysis. Conclusions: We have shown the inaccuracy of one of the recently proposed models. We have added the possibility of determining the dropout probability into the second model, otherwise this model overestimates the probabilities calculated.

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X-STR decaplex study on the population of Czech Republic

2013

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Sample containing 234 unrelated males and 197 unrelated females from Czech Republic was genotyped using an X-STR decaplex system in the following loci: DXS6789, DXS6809, DXS7132, DXS7133, DXS7423, DXS8378, DXS9898, DXS9902, GATA172D05, and GATA31E08. The linkage disequilibrium was observed between DXS6789 and DXS6809. The combined power of discrimination was 0.9999999998 (females) and 0.999998 (males). The mean exclusion chance was 0.999995 (trios) and 0.9998 (duos). This work presents the first population data for X-STR decaplex in Central Europe.

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Allele frequency data for 17 short tandem repeats in a Czech population sample

Cited by 12 publications

References 18 publications

Investigator® Argus X‐12 study on the population of Czech Republic: Comparison of linked and unlinked X‐STRs for kinship analysis

Investigator® Argus X‐12 study on the population of Czech Republic: Comparison of linked and unlinked X‐STRs for kinship analysis

Stochastic Models for Low Level DNA Mixtures

X-STR decaplex study on the population of Czech Republic

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