Allele frequencies of 23 short tandem repeat loci in the Vietnamese Kinh population

Vu, Thi Thanh Hoan; Thu, Thi; Nguyễn, Thị Hoài; Luyen, Quoc Hai

doi:10.1016/j.fsir.2021.100210

Cited by 1 publication

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“…Consistent with previous studies, TPOX was the least discriminative locus. While in this study FGA was the most informative locus, other studies have supported PentaE as the most powerful locus ( Rodriguez et al, 2015 ; Sheng et al, 2018 ; Castillo et al, 2019 ; Chen et al, 2019 ; Naji et al, 2019 ; Shrivastava et al, 2019 ; Vu et al, 2021 ). Overall, the 23 STR loci in Verifiler TM plus PCR amplification kit could be valuable for forensic investigation in Thailand and Laos.…”

Section: Resultscontrasting

confidence: 55%

Genetic Structure and Forensic Utility of 23 Autosomal STRs of the Ethnic Lao Groups From Laos and Thailand

et al. 2022

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The Lao Isan and Laotian are the major groups in the area of present-day northeastern Thailand and Laos, respectively. Several previous genetic and forensic studies indicated an admixed genetic structure of Lao Isan with the local Austroasiatic speaking groups, e.g. Khmer, whereas there is a paucity of reporting Laotian’s forensic short tandem repeats (STRs). Here, we newly generated 451 genotypes of seven Lao Isan and three Laotian populations (two Lao Lum and one Lao Thoeng) using 23 autosomal STRs embedded in VerifilerTM plus PCR Amplification kit. We reported allelic frequency and forensic parameters in different dataset: combined ethnic Lao groups, combined Lao Isan populations and combined Laotians. Overall, the forensic parameter results indicate that this set of STRs is suitable for forensic investigation. The anthropological results revealed the genetic homogeneity of Tai-Kadai speaking Lao groups from Thailand and Laos, consistent with previous studies, while the Austroasiatic speaking groups from southern Laos showed genetic relatedness to both Lao Isan and Khmer. In sum, STRs allelic frequency results can provide the genetic backgrounds of populations which is useful for anthropological research and also strengthens the regional forensic database in both countries.

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