All‐cis 5,11,14‐20:3 acid: Podocarpic acid or sciadonic acid?

Chemical profiling of Portuguese Pinus pinea L. nuts

“…Δ5‐UPIFA are characteristic and systematic components of gymnosperm seed oils 7. While sciadonic acid occurs (along with minor amounts of 5,11–20:2 and 11,14–20:2 acids) in the seed lipids of all gymnosperm species containing Δ5‐UPIFA, pinolenic acid is restricted to certain families32 and presents a higher interspecific variation in the genus Pinus 7. For instance, compared with the data reported for P. koraiensis ,33 P. pinea seeds show a large discrepancy in pinolenic acid concentration (0.3 vs 15%).…”

Metabolic characterization of sciadonic acid (5c,11c,14c‐eicosatrienoic acid) as an effective substitute for arachidonate of phosphatidylinositol

“…In this study, we investigated the metabolism of sciadonic acid by fatty acid desaturase. Under our assay conditions, where D9, D6 and D5 desaturase exerts its activity, substantial amounts of 20:4 were not formed from [1][2][3][4][5][6][7][8][9][10][11][12][13][14] C]polymethylene-interrupted 20:3. Although our data is limited for the liver microsome, several investigations [31,32] have reported evidence that fatty acid desaturases in rat liver and testis could not desaturate sciadonic acid to arachidonic acid under in vivo conditions using [ 14 C]sciadonic acid [32].…”

“…Therefore, we used this mixture of polymethylene-interrupted 20:3 for fatty acid desaturase assay. The yields of [1][2][3][4][5][6][7][8][9][10][11][12][13][14] C]polymethylene-interrupted 20:3 from [1-14 C]arachidonic acid under our system was 6.5%. D9, D6 and D5 desaturase activities of rat liver microsomes were investigated using radiolabeled stearic acid, linoleic acid and dihomo-g-linolenic acid, respectively.…”