Alkyl-Substituted Cucurbit[6]uril Bridged β-Cyclodextrin Dimer Mediated Intramolecular FRET Behavior

Abstract

A novel triazolyl bridged cucurbituril (CB)−cyclodextrin (CD) dimer was synthesized via click reaction of monopropargyl modified octamethylcucurbit[6]uril and mono-6-azido-β-cyclodextrin. Moreover, it could form stable supramolecular inclusion complexes possessing efficient fluorescence resonance energy transfer, which benefited from the fact that CD and CB can bind amantadine-and pyridinium-containing fluorophores simultaneously. The supramolecular inclusion complex behaviors were investigated by NMR spectroscopy, UV−vis absorption, and fluorescence spectroscopy.

Purely organic light-harvesting phosphorescence energy transfer by β-cyclodextrin pseudorotaxane for mitochondria targeted imaging

“…Additionally, taking advantage of the strong binding ability between β-CD and adamantane, 51,52 HA-ADA was introduced into this PET system in aqueous solution to interact with the β-CD unit. Learning from previous reports, 58,59 hyaluronic acid (HA) that possesses excellent aqueous solubility, biocompatibility, and biodegradability can specifically recognize HA receptors (CD44 and RHAMM receptors) over expressed on the tumor cell surface in cancer metastasis.…”

Asymmetric Cyclodextrin-Dimer-Involved Nanoassemblies by Selective Host–Guest Interactions: Concentration-Dependent Morphology Evolution and Light-Regulated Biomedical Applications

“…Similarly, a planar triphenylbenzene core bridged β-CD trimer was also synthesized by “click” reaction to investigate the influence of temperature, acidity, and competitive guests on the self-inclusion and dissociation transition . Other kinds of triazolyl bridged cucurbituril (CB)–CD dimer as well as CD–CD and CD–Ad dimers were fabricated to investigate the host–guest interaction-induced self-assembly properties. , …”

A Complete Study of Synthesis of Glycoluril and Its Derivative by Using Different Greener Acids

“…[10][11][12][13][14][15][16][17][18][19] The fascinating macrocyclic compound cucurbiturils (CB[n]), whose skeleton is made up of glycoluril ring moieties, has received a lot of attention. [20][21][22][23][24][25][26][27][28] Bambusurils also have glycoluril as their monomer unit. [29,30] It has been reported that glyoxal and their derivatives can be converted into glycolurils by condensing them with urea using acids like H 2 SO 4 , HCl, H 3 PO 4 , P 2 O 5 and CCl 3 COOH as catalysts.…”