Alkaloids from Choisya ternata and their human antiplatelet activity

Wahab, Abdul; Rahayu, I; Wong, Nikki Siu Hai; Santos-Martínez, María José; Boylan, Fábio

doi:10.1055/s-0032-1320957

Cited by 2 publications

(1 citation statement)

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“…Choisya ternata is an ornamental plant with leaves and white flowers which resemble an orange tree. Due to this, its English name is "Mexican orange"; however, in Mexican culture can be identified by other popular namesm such as "flor de clavo", "clavillo" or "clavo de olor" [106]. As a peculiarity, this plant is a member of the Rutaceae family and is native to the central and southern mountains of México [85].…”

Section: Choisya Ternata Kunthmentioning

confidence: 99%

Mexican Plants and Derivates Compounds as Alternative for Inflammatory and Neuropathic Pain Treatment—A Review

Quiñonez-Bastidas

Navarrete

2021

Plants

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Despite the availability of many anti-pain drugs, in the form of NSAIDs, steroids, gabapentinoids, opioids, and antidepressants, in this study we address the natural compounds belonging to the group of Mexican medicinal plants or “Mexican folk medicine”, used for pain management in Mexico. Our interest in this subject is due to the growing idea that “natural is harmless” and to the large number of side effects exhibited in pharmacotherapy. The objective of this review was to document the scientific evidence about Mexican medicinal plants and their derivatives used for inflammatory and neuropathic pain treatment, as well as the mechanisms of action implicated in their antinociceptive effects, their possible adverse effects, and the main pharmacological aspects of each plant or compound. Our data review suggested that most studies on Mexican medicinal plants have used inflammatory experimental models for testing. The anti-pain properties exerted by medicinal plants lack adverse effects, and their toxicological assays report that they are safe to consume; therefore, more studies should be performed on preclinical neuropathic pain models. Moreover, there is no convincing evidence about the possible mechanisms of action involved in the anti-pain properties exerted by Mexican plants. Therefore, the isolation and pharmacological characterization of these plant derivatives’ compounds will be important in the design of future preclinical studies.

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Section: Choisya Ternata Kunthmentioning

confidence: 99%