Alkaline phosphatase activity of polymorphonuclear leukocytes in relation to oral contraceptives

Sammour, Mohamed B.; Hilal, Samir O.

doi:10.1016/0002-9378(69)90581-x

Cited by 6 publications

(6 citation statements)

References 4 publications

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“…Sammour and Hilal (1969) have also noted elevated N.A.P. similar to those observed in pregnancy were found in most individuals receiving oral contraceptives and a variable response with different agents was observed.…”

Section: Discussionmentioning

confidence: 51%

“…values in the menstrual cycle were first noted by Bore1 et al (1958) who demonstrated a rise during the second week. Sammour and Hilal (1969) suggested that there might be a peak on the fifth day and a second during the last week of the cycle. Sammour and Hilal (1969) suggested that there might be a peak on the fifth day and a second during the last week of the cycle.…”

Section: Discussionmentioning

confidence: 99%

“…Gordon and Hunter (1965) also defined a 4--> prgonal I< hasdl ' F total ur,nary oertrogenr 09 24 hrs neutrophilr midcycle peak. Sammour and Hilal (1969) suggested that there might be a peak on the fifth day and a second during the last week of the cycle. Bauer-Sic (1966) also noted a second peak but, in contrast to the present study, the first enzyme peak was always more prominent than the second.…”

Section: Discussionmentioning

confidence: 99%

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The Variation of Neutrophil Alkaline Phosphatase During the Menstrual Cycle

Cochrane

Weatherall

1972

BJOG

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The variation of neutrophil alkaline phosphatase (N.A.P.) activity during the menstrual cycle was investigated in 9 normal females, 7 females taking various oral contraceptives, and an infertile female receiving gonadotrophin therapy. The day to day variation of N.A.P. values in 2 males and the range of values in 272 normal adults and 72 pregnant women were also determined. Adult females have a significantly higher N.A.P. value than males. Normal females show two physiological peaks of N.A.P. activity during the menstrual cycle, the first at ovulation, and a second in the luteal phase. The variation of N.A.P. in the menstrual cycle is probably related to fluctuating oestrogen levels. In most cases these peaks are not affected by oral contraceptive administration which is often associated with high enzyme levels as in pregnancy. The N.A.P. response varies with different oral contraceptives. The present study provides further evidence that combined oral contraceptive preparations do not always inhibit ovulation. Daily N.A.P. estimations should prove useful in the assessment of menstrual function, and the investigation of infertility.

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Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The Variation of Neutrophil Alkaline Phosphatase During the Menstrual Cycle

Cochrane

Weatherall

1972

BJOG

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“…Following the observations of Wachstein (19) it has been mainly used in the differential diagno sis of hematological diseases. However, during the last years, more and more papers have dealt with the endocrine relations of this enzyme (1,2,6,12,15).…”

mentioning

confidence: 99%

“…GAP activity is higher in adult females than in males of similar age (12), and its peak appears during the men struation cycle at the time of the ovulation (2). Increased enzyme activity was observed after exogenous estrogen administration (1) and after oral contra ceptives (15).…”

mentioning

confidence: 99%

Changes in the Alkaline Phosphatase Activity of Granulocytes from the First to the Sixth Day of Life in Newborns

Nagy¹,

Szabó²,

Csába³

1975

Neonatology

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GAP activity was studied in 40 newborns, from the first to the sixth day of life after normal pregnancy and labor. Evaluation of GAP activity was performed in stained blood smears by the method of Kaplow. The results of this study indicate, that GAP activity on the first day of life was higher (121.0 ± 16.7 GAP score) than on the sixth day (68.6 ± 12.0 GAP score). The authors, discussing the possible cause of the increased alkaline phosphatase activity in granulocytes during the first day of life, cannot exclude the possibility that the GAP activity is influenced by estrogens of maternal origin.

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Increased Susceptibility to Infection Due to Dysfunction of Granulocytes

Nathan

Baehner

1970

Blood Cells as a Tissue

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Alkaline phosphatase activity of polymorphonuclear leukocytes in relation to oral contraceptives

Cited by 6 publications

References 4 publications

The Variation of Neutrophil Alkaline Phosphatase During the Menstrual Cycle

The Variation of Neutrophil Alkaline Phosphatase During the Menstrual Cycle

Changes in the Alkaline Phosphatase Activity of Granulocytes from the First to the Sixth Day of Life in Newborns

Increased Susceptibility to Infection Due to Dysfunction of Granulocytes

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