Algorithms for calculating and correcting blood-gas and acid-base variables

Gabel, Ronald A.

doi:10.1016/0034-5687(80)90116-4

Cited by 37 publications

(22 citation statements)

References 36 publications

(18 reference statements)

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“…We compared the calculated O 2 saturations with and without the pH and PCO 2 corrections (Gabel 1980). The results were not affected by more than 0.4 sat% at any O 2 level, despite the progressively increasing O 2 content in the gas mixtures.…”

Section: Discussionmentioning

confidence: 94%

“…The Tukey HSD test confirmed that each method and each O 2 concentration differed from all others, as was anticipated from the experimental design. The main effect of experimental (Gabel 1980) treatment was included in the analysis, although each experimental treatment value can be compared only with its respective control at each O 2 concentration for each method.…”

Section: Resultsmentioning

confidence: 99%

“…A significance level of P < 0.05 was accepted throughout the study. Table 1 shows the mean O 2 saturation values for the ABL, COOX, and LEX analytical methods, with the calculated Siggaard-Anderson (1974) saturation value corrected for PCO 2 and pH (Gabel 1980). The value for each experimental gas and N 2 dilution mixture is listed immediately beneath its respective baseline control value.…”

Section: Discussionmentioning

confidence: 99%

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Blood oxygen saturation measured in the presence of a mixture of cyclopropane, Sulfur hexafluoride, and ethane

Forte

Burse

Cymerman

1996

European Journal of Applied Physiology

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Some anesthetic gases interfere with the determination of blood O2 values. We evaluated, for its potential for such interference, a gas mixture containing (v/v) approximately 70% ethane, 20% sulfur hexafluoride, and 10% cyclopropane, as is currently used in trace amounts to determine ventilation-perfusion (v/Q) ratios. Normal human blood samples were first tonometered with control gas mixtures containing (v/v): (1) 20.9% O2, 0.04% CO2; (2) 16.0% O2, 4.0% CO2; and (3) 9.9% O2, 7.8% CO2. A large quantity (20.9%) of the v/Q mixture was blended experimentally into the control mixture and the tonometry repeated. The entire experiment was then repeated substituting pure N2 for the v/Q mixture as a dilution control. O2 values were determined by three methods: (1) a polarographic electrode, ABL-300 (ABL); (2) a spectrophotometric method, Co-Oximeter (COOX); and (3) a galvanic cell, Lex-O2-Con (LEX). The v/Q gas mixture lowered significantly all measured LEX values by 2.5-3.6 saturation percent (sat%), but showed no effect, dilution or otherwise, on the O2 values determined by the COOX and ABL methods. The N2 dilution lowered the LEX values by an average of only 0.9 sat%; the ABL and the COOX were approximately 0.6 sat% lower. We therefore suggest that, if any of these O2 measurement methods are used in the presence of the v/Q mixture, baseline O2 values should be determined both before and after injection of the mixture into the bloodstream, prior to performing other experimental manipulations. The difference between the two values, if any, can then be used to interpret subsequent results.

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Section: Discussionmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Blood oxygen saturation measured in the presence of a mixture of cyclopropane, Sulfur hexafluoride, and ethane

Forte

Burse

Cymerman

1996

European Journal of Applied Physiology

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“…Sot can be calculated from vPo2 by several algorithms reported previously (LABEL, 1980). We used the algorithm reported by SAsAI et al (1984) which, to the best of our knowledge, provides exact expression for the "standard" oxygen hemoglobin equilibrium curve reported by SEVERINGHAUS (1979).…”

Section: Calculations and Iterationsmentioning

confidence: 99%

“…By combining Eq. 2 with the following equations for calculating P0237 from vPo237 and VPo2T from Po2T (LABEL, 1980;SEVERINGHAUS, 1979), Vol. 36, No.…”

Section: Calculations and Iterationsmentioning

confidence: 99%

New equations to calculate temperature correction factors for Po2 in human blood.

Inaba¹,

Ohwada²,

Sato³

et al. 1986

Jpn.J.Physiol

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Effects of hemoglobin concentration (Hb), pH, and body temperature (T) on the relationships between d log Poz/d T and Pot were studied by means of a mathematical model using a Newton-Raphson iteration method. The functions between d log Poz/d T and Poz were affected by the above three factors. New equations considering the effects of Hb, pH, and T were proposed by modifying the equation reported by Severinghaus: where fB is the Bohr factor. The above equations provided values of d log Poz/d T which fit closely to those obtained by the complex iteration method with maximum differences of less than 1.3 x 10 -3 at T= 27, indicating that maximum errors for Poz at T (PozT) are less than 3.0°c at T=27 and that our equations can be applied over a wide range of Hb, pH37 and T.

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Venous Bicarbonate Correlates Linearly With Arterial Base Deficit Only If pH Is Constant

Lujan¹

2006

Arch Surg

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Algorithms for calculating and correcting blood-gas and acid-base variables

Cited by 37 publications

References 36 publications

Blood oxygen saturation measured in the presence of a mixture of cyclopropane, Sulfur hexafluoride, and ethane

Blood oxygen saturation measured in the presence of a mixture of cyclopropane, Sulfur hexafluoride, and ethane

New equations to calculate temperature correction factors for Po2 in human blood.

Venous Bicarbonate Correlates Linearly With Arterial Base Deficit Only If pH Is Constant

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