Alginate/gum arabic-based biomimetic hydrogel enriched with immobilized nerve growth factor and carnosine improves diabetic wound regeneration

Keykhaee, Maryam; Rahimifard, Mahban; Najafi, Alireza; Baeeri, Maryam; Abdollahi, Mohammad; Mottaghitalab, Fatemeh; Farokhi, Mehdi; Khoobi, Mehdi

doi:10.1016/j.carbpol.2023.121179

Cited by 12 publications

(2 citation statements)

References 119 publications

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“…The band recorded at 1039 cm −1 was due to the saccharide structure (C– O –C). The C–O bending of GA was assigned at 1419 cm-1, indicating the presence of both polymers in the AG hydrogel [ 45 , 46 ]. In the spectrum of AG-P, the signature peak at 3280–3401 cm −1 , corresponding to the O–H and N–H stretching vibrations, was amplified significantly and revealed as a single broad peak.…”

Section: Resultsmentioning

confidence: 99%

Polysaccharide-based hydrogel enriched by epidermal growth factor peptide fragment for improving the wound healing process

Keykhaee,

Sorouri,

Rahimifard

et al. 2023

Heliyon

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Section: Resultsmentioning

confidence: 99%

Polysaccharide-based hydrogel enriched by epidermal growth factor peptide fragment for improving the wound healing process

Keykhaee,

Sorouri,

Rahimifard

et al. 2023

Heliyon

Self Cite

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“…Alginate is an abundant natural polysaccharide derived from seaweed and found in the cell wall of brown algae, consisting of β(1,4)-linked D-mannuronic acid (M) and α(1,4)-L-guluronic acid (G) as the repeating units [81]. Alginate exists in the form of salts, including calcium, magnesium, and sodium salts.…”

Section: Sodium Alginate (Sa)-based Chdsmentioning

confidence: 99%

Nature-Derived Polysaccharide-Based Composite Hydrogels for Promoting Wound Healing

Lee,

Jung,

Lee

et al. 2023

IJMS

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Numerous innovative advancements in dressing technology for wound healing have emerged. Among the various types of wound dressings available, hydrogel dressings, structured with a three-dimensional network and composed of predominantly hydrophilic components, are widely used for wound care due to their remarkable capacity to absorb abundant wound exudate, maintain a moisture environment, provide soothing and cooling effects, and mimic the extracellular matrix. Composite hydrogel dressings, one of the evolved dressings, address the limitations of traditional hydrogel dressings by incorporating additional components, including particles, fibers, fabrics, or foams, within the hydrogels, effectively promoting wound treatment and healing. The added elements enhance the features or add specific functionalities of the dressings, such as sensitivity to external factors, adhesiveness, mechanical strength, control over the release of therapeutic agents, antioxidant and antimicrobial properties, and tissue regeneration behavior. They can be categorized as natural or synthetic based on the origin of the main components of the hydrogel network. This review focuses on recent research on developing natural polysaccharide-based composite hydrogel wound dressings. It explores their preparation and composition, the reinforcement materials integrated into hydrogels, and therapeutic agents. Furthermore, it discusses their features and the specific types of wounds where applied.

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Functionalised biomaterials as synthetic extracellular matrices to promote vascularisation and healing of diabetic wounds

Browne,

Petit,

Quondamatteo

2023

Cell Tissue Res

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Alginate/gum arabic-based biomimetic hydrogel enriched with immobilized nerve growth factor and carnosine improves diabetic wound regeneration

Cited by 12 publications

References 119 publications

Polysaccharide-based hydrogel enriched by epidermal growth factor peptide fragment for improving the wound healing process

Polysaccharide-based hydrogel enriched by epidermal growth factor peptide fragment for improving the wound healing process

Nature-Derived Polysaccharide-Based Composite Hydrogels for Promoting Wound Healing

Functionalised biomaterials as synthetic extracellular matrices to promote vascularisation and healing of diabetic wounds

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