Algae induce siderophore biosynthesis in the freshwater bacterium Cupriavidus necator H16

Kurth, Colette; Wasmuth, Ina; Wichard, Thomas; Pohnert, Georg; Nett, Markus

doi:10.1007/s10534-018-0159-6

Cited by 14 publications

(7 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… References Ornithine N -hydroxylases Pseudobactin Pseudomonas sp. B10 Ornithine PsbA Q9F8X0, AAG27518 Ambrosi et al ( 2000 ) Pyoverdine PAO Pseudomonas aeruginosa PAO1 Ornithine PvdA Q51548, WP_003114509 Ge and Seah ( 2006 ) Ornibactin Burkholderia cepacia K56–2 Ornithine PvdA Bc O51940, AAB94515 Sokol et al ( 1999 ) Cupriachelin Cupriavidus necator H16 Ornithine PvdA Re Q0K0K9, CAJ96465 Kurth et al ( 2019 ) Taiwachelin Cupriavidus taiwanensis Ornithine TaiO YP_002007894, WP_012356056 Kreutzer and Nett ( 2012 ) Malleobactin Burkholderia pseudomallei Ornithine MbaA Bp2 YP_001066209, WP_004535763 Alice et al ( 2006 ) Malleobactin A, B, C, D Burkholderia thailandensis Ornithine MbaC WP_011402367 Franke et al ( 2013 ) Ferrichrome Aspergillus nidulans Ornithine SidA Q7Z8P5, AAP56238 Eisendle et al ( 2003 ) Ferricrocin, ferrichrome Aspergillus fumigatus Ornithine SidA E9QYP0, AAT84594 Hissen et al ( 2005 ); Chocklett and Sobrado ( 2010 ) Deferriferrichrysin Aspergillus oryzae Ornithine Dff Q2TZB2, BAC15565 Yamada et al ( 2003 ) ...…”

Section: Nmos Involved In Siderophore Biosynthesismentioning

confidence: 99%

Flavin-dependent N-hydroxylating enzymes: distribution and application

Mügge

Heine

Baraibar

et al. 2020

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

Amino groups derived from naturally abundant amino acids or (di)amines can be used as "shuttles" in nature for oxygen transfer to provide intermediates or products comprising NO functional groups such as N-hydroxy, oxazine, isoxazolidine, nitro, nitrone, oxime, C-, S-, or N-nitroso, and azoxy units. To this end, molecular oxygen is activated by flavin, heme, or metal cofactorcontaining enzymes and transferred to initially obtain N-hydroxy compounds, which can be further functionalized. In this review, we focus on flavin-dependent N-hydroxylating enzymes, which play a major role in the production of secondary metabolites, such as siderophores or antimicrobial agents. Flavoprotein monooxygenases of higher organisms (among others, in humans) can interact with nitrogen-bearing secondary metabolites or are relevant with respect to detoxification metabolism and are thus of importance to understand potential medical applications. Many enzymes that catalyze N-hydroxylation reactions have specific substrate scopes and others are rather relaxed. The subsequent conversion towards various NO or N-N comprising molecules is also described. Overall, flavin-dependent N-hydroxylating enzymes can accept amines, diamines, amino acids, amino sugars, and amino aromatic compounds and thus provide access to versatile families of compounds containing the NO motif. Natural roles as well as synthetic applications are highlighted. Key points • NO and N-N comprising natural and (semi)synthetic products are highlighted. • Flavin-based NMOs with respect to mechanism, structure, and phylogeny are reviewed. • Applications in natural product formation and synthetic approaches are provided.

show abstract

Section: Nmos Involved In Siderophore Biosynthesismentioning

confidence: 99%

Flavin-dependent N-hydroxylating enzymes: distribution and application

Mügge

Heine

Baraibar

et al. 2020

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

show abstract

“…Such an iron-dependent mutualism has been previously reported between alga Dunaliella bardawil and Halomonas sp [ 44 ]., diatom Navicula pelliculosa and Cupriavidus necator [ 45 ], marine alga Scrippsiella trochoidea and Marinobacter sp [ 37 ]., freshwater alga Chlorella variabilis and Idiomarina loihiensis [ 46 ]. Previously, a commensal association between R. pickettii and C. sorokiniana has been reported under nutrient-sufficient photoautotrophic conditions [ 47 ].…”

Section: Resultsmentioning

confidence: 99%

“…This work demonstrated that extracellular iron concentration influenced the ferrireductase-mediated iron uptake in C. sorokiniana , which also affected the dye reduction pathway. Bacterial siderophores have a major influence on iron cycling and shaping phototrophic communities in aquatic ecosystems [ 45 ]. In the high-nutrient, low-carbon (HNLC) regions of open oceans, bacterial siderophores have been known to alleviate iron limitation, which benefits algae [ 69 , 82 ].…”

Section: Resultsmentioning

confidence: 99%

Iron-dependent mutualism between Chlorella sorokiniana and Ralstonia pickettii forms the basis for a sustainable bioremediation system

Rawat

Sharma

Poria

et al. 2022

ISME Communications

View full text Add to dashboard Cite

Phototrophic communities of autotrophic microalgae and heterotrophic bacteria perform complex tasks of nutrient acquisition and tackling environmental stress but remain underexplored as a basis for the bioremediation of emerging pollutants. In industrial monoculture designs, poor iron uptake by microalgae limits their productivity and biotechnological efficacy. Iron supplementation is expensive and ineffective because iron remains insoluble in an aqueous medium and is biologically unavailable. However, microalgae develop complex interkingdom associations with siderophore-producing bacteria that help solubilize iron and increase its bioavailability. Using dye degradation as a model, we combined environmental isolations and synthetic ecology as a workflow to design a simplified microbial community based on iron and carbon exchange. We established a mutualism between the previously non-associated alga Chlorella sorokiniana and siderophore-producing bacterium Ralstonia pickettii . Siderophore-mediated increase in iron bioavailability alleviated Fe stress for algae and increased the reductive iron uptake mechanism and bioremediation potential. In exchange, C. sorokiniana produced galactose, glucose, and mannose as major extracellular monosaccharides, supporting bacterial growth. We propose that extracellular iron reduction by ferrireductase is crucial for azoreductase-mediated dye degradation in microalgae. These results demonstrate that iron bioavailability, often overlooked in cultivation, governs microalgal growth, enzymatic processes, and bioremediation potential. Our results suggest that phototrophic communities with an active association for iron and carbon exchange have the potential to overcome challenges associated with micronutrient availability, while scaling up bioremediation designs.

show abstract

“…Algae stimulate the production of siderophore, i.e., high-affinity Fe-chelating compounds secreted by bacteria by producing organic acids that photolyzes these siderophores and thereby triggers iron assimilation in very low iron and nitrogen conditions chiefly in the waterlogged or aquatic environment. A recent study valorized the freshwater microalgae Navicula pelliculosa induced siderophore biosynthesis in the bacterium Cupriavidus necator H16 (Kurth et al, 2019). Another experiment that cultivated microalgae in black water (toilet wastewater) concluded that microalgae biofertilizer works similar to inorganic fertilizer but emits more N 2 O and CO 2 due to nitrification pathways.…”

Section: Biofertilizermentioning

confidence: 99%

Valorization of Wastewater Resources Into Biofuel and Value-Added Products Using Microalgal System

et al. 2021

View full text Add to dashboard Cite

Wastewater is not a liability, instead considered as a resource for microbial fermentation and value-added products. Most of the wastewater contains various nutrients like nitrates and phosphates apart from the organic constituents that favor microbial growth. Microalgae are unicellular aquatic organisms and are widely used for wastewater treatment. Various cultivation methods such as open, closed, and integrated have been reported for microalgal cultivation to treat wastewater and resource recovery simultaneously. Microalgal growth is affected by various factors such as sunlight, temperature, pH, and nutrients that affect the growth rate of microalgae. Microalgae can consume urea, phosphates, and metals such as magnesium, zinc, lead, cadmium, arsenic, etc. for their growth and reduces the biochemical oxygen demand (BOD). The microalgal biomass produced during the wastewater treatment can be further used to produce carbon-neutral products such as biofuel, feed, bio-fertilizer, bioplastic, and exopolysaccharides. Integration of wastewater treatment with microalgal bio-refinery not only solves the wastewater treatment problem but also generates revenue and supports a sustainable and circular bio-economy. The present review will highlight the current and advanced methods used to integrate microalgae for the complete reclamation of nutrients from industrial wastewater sources and their utilization for value-added compound production. Furthermore, pertaining challenges are briefly discussed along with the techno-economic analysis of current pilot-scale projects worldwide.

show abstract

Algae induce siderophore biosynthesis in the freshwater bacterium Cupriavidus necator H16

Cited by 14 publications

References 50 publications

Flavin-dependent N-hydroxylating enzymes: distribution and application

Flavin-dependent N-hydroxylating enzymes: distribution and application

Iron-dependent mutualism between Chlorella sorokiniana and Ralstonia pickettii forms the basis for a sustainable bioremediation system

Valorization of Wastewater Resources Into Biofuel and Value-Added Products Using Microalgal System

Contact Info

Product

Resources

About