Alcohol intake and cardiovascular mortality in hypertensive patients: report from the Department of Health Hypertension Care Computing Project

Palmer, Alison; Fletcher, A. E.; Bulpitt, C. J.; Beevers, D. G.; Coles, E C; Ledingham, J. G. G.; Petrie, J C; Webster, J.; Dollery, C T

doi:10.1097/00004872-199509000-00004

Cited by 63 publications

(37 citation statements)

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“…3 Alcohol consumption is linearly related to increased blood pressure, 4,5 and the CVD risk also linearly increases according to the blood pressure level. 6 Thus, several previous studies have investigated the relationships among alcohol consumption, hypertension and CVD risk in hypertensive patients, [7][8][9] but few studies were performed in the general population including both hypertensives and non-hypertensives.…”

Section: Introductionmentioning

confidence: 99%

Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

et al. 2012

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The relationship between alcohol consumption and the risk for cardiovascular disease (CVD) is U-shaped, whereas alcohol drinking is linearly associated with blood pressure, and the CVD risk also increases linearly according to blood pressure level. Accordingly, we investigated the net effect of alcohol consumption and hypertension on CVD and its subtypes in this study. A 13-year prospective study of 2336 Japanese men who were free from CVD was performed; ex-drinkers were excluded. The participants were divided into eight groups classified by the combination of the presence of hypertension (systolic/diastolic blood pressure ≥140/90 mm Hg) and alcohol consumption (never-, current- (light, moderate and heavy) drinkers). Multivariate-adjusted hazard ratios (HRs) for the incidence of CVD, coronary artery disease (CAD) and stroke due to the combination of hypertension and alcohol consumption were calculated and compared with non-hypertensive never-drinkers. The HRs for CVD and its subtypes were higher in hypertensives than those in non-hypertensives; in hypertensives without medication for hypertension, the relationship between alcohol consumption and the risks for CVD and CAD was U-shaped, with the highest and most significant increase in never-drinkers. The risk for total stroke was the highest in heavy-drinkers, which was significant. In non-hypertensives, there was no evident increase or decrease in the HRs for CVD and its subtypes in drinkers. Accordingly, controlling blood pressure is important to prevent CVD. In hypertensives, heavy drinking should be avoided to prevent CVD, although light-to-moderate drinking could be protective for CAD. Furthermore, in non-hypertensives, drinkers may need to continuously monitor their blood pressure.

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Section: Introductionmentioning

confidence: 99%

Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

et al. 2012

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“…16) Light to moderate drinking has been shown to be associated with a reduced risk of ischemic stroke, coronary heart disease, and mortality. [24][25][26][27][28][29] It has been suggested that the beneficial influences of alcohol intake on lipids and haemostatic factors may explain this association. [30][31][32][33] Some authors have indicated that red wine may enhance endothelial nitric oxide synthase function and antagonize the development of endothelial dysfunction and atherosclerosis.…”

Section: Discussionmentioning

confidence: 99%

Association between Alcohol Consumption and Hypertension

Son¹

2011

J Korean Soc Hypertens

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“…In an early study investigating alcohol and CVD mortality among hypertensive men, male drinkers with hypertension had a reduced risk of stroke mortality as well as a possible reduction in CHD mortality [43]. Total mortality was not significantly different between drinkers and nondrinkers due to an increased risk of death from noncirculatory causes with increasing alcohol consumption.…”

Section: Treatment: Prospective Studies Of Alcohol Cardiovascular DImentioning

confidence: 97%

Alcohol as a Risk Factor and Treatment Target for Hypertension

Sesso

2010

Curr Cardio Risk Rep

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The prevalence of hypertension has risen precipitously in recent decades, reinforcing the need to improve both primary and secondary prevention efforts. The quantity of alcohol consumed may pose either benefits or risks on blood pressure (BP) and hypertension. This review describes how alcohol is currently integrated into hypertension clinical guidelines, the mechanisms through which alcohol may affect BP, and the epidemiologic studies evaluating the association between alcohol, changes in BP, and the risk of developing hypertension. This review considers the effects of total alcohol intake, plus specific types and patterns of alcohol intake. It also examines studies examining alcohol intake among existing hypertensive patients for the risk of mortality and incident cardiovascular disease. Based upon the current evidence on alcohol, BP, and hypertension, men and women currently consuming light-to-moderate amounts of alcohol should maintain their intake in terms of BP levels and hypertension prevention and treatment.

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Alcohol intake and cardiovascular mortality in hypertensive patients: report from the Department of Health Hypertension Care Computing Project

Cited by 63 publications

References 0 publications

Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study

Association between Alcohol Consumption and Hypertension

Alcohol as a Risk Factor and Treatment Target for Hypertension

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