Albumin-bound substances - a new target in liver failure therapy

MARS procedure as a bridge to combined liver–kidney transplantation in severe chromium–copper acute intoxication: a paediatric case report

“…The solution is constantly circulating and regenerating in the column system, which contains activated charcoal and ion resin. This system allows selective removal of the protein‐bound toxins, such as any excess of bilirubin, phenols, thiols, bile acids, ammonium, aromatic amino acids, lactates and ‘false’ neurotransmitters, which are accumulated in cases of severe damage of liver tissue, leading to hepatic coma or hepato‐renal syndrome (2, 3). In using the MARS procedure, the intention is to achieve toxin removal, stabilization of homeostasis and the creation of a ‘bridge’ for patients awaiting urgent liver transplants (4, 5).…”