Albinism in childhood: a flash VEP and ERG study.

Monte Carlo model for studying the effects of melanin concentrations on retina light absorption

“…Previous studies in young children have indicated that albino subjects had stronger and faster ERG signals than normal pigmented subjects [4]. Similar results were obtained in small animal [5].…”

Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials

“…Smaller b-wave amplitudes were found in patients with higher fundus pigmentation, which led to the hypothesis that this decrease could be related to a higher ocular resistance caused by melanin [52,53]. Russell-Eggitt et al [44] recorded ERGs in ocular and oculocutaneous albino Fig. 11 Averages of scotopic and photopic VEP waveforms obtained in four Long-Evans rats (solid lines) and four Wistar rats (dotted lines) at the ages of 1.5 and 7 months.…”

“…As a consequence of the reduced number of rods, an impaired post-receptoral response would also be expected. On the other hand, there are several reports that ERG amplitudes are larger in albino humans [44,[51][52][53]. Therefore, the purpose of this study was to compare the single aspects of retinal function of two closely related strains of pigmented and albino rats by comparing several ERG parameters.…”

Electrophysiological assessment of visual pathway function in infants

“…t We do not favour rou tine use of sedation or anaesthesia as these procedures carry risks, and can alter the YEP (the latter can affect the ERG also), thus complicating clinical interpretation of any detected response changes. In our experience, it is diagnostically more advantageous (and cost effective) to average skin ERGs and VEPs together in order to get an estimate of both gross retinal function (from the ERG) and macular pathway function (from the YEP) in a single recording session lasting [30][31][32][33][34][35][36][37][38][39][40] A. KRISS AND 1. RUSSELL-EGGITT conditions is tested first; flash stimulation is then per formed, first under darkened conditions then photopically.…”