Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver

Arif, Sajad; Shams-ul-Bari,; Wani, Nazir A.; Zargar, Showkat Ahmad; Wani, Mohd Yaqoob; Tabassum, Rehana; Hussain, Zahoor; Baba, Asif Nazir; Lone, Riyaz Ahmad

doi:10.1016/j.ijsu.2008.08.003

Cited by 135 publications

(82 citation statements)

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“…The exact cause of this is unknown but in our opinion, this may be due to lack of cooperation of patients in taking Albendazole. In several studies it is confirmed that preoperative and postoperative use of Albendazole can reduce the risk of recurrence significantly (Arif et al 2008;bildik et al 2007). We think the patients should become more informed about the importance of taking their medication and more communication is required between physicians and patients to improve the treatment results.…”

Section: Discussionmentioning

confidence: 96%

A retrospective survey of human hydatidosis based on hospital records during the period of 10 years

et al. 2012

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Hydatid cyst is a parasitic infection that is widely seen endemically in the Middle East countries. We studied hydatid cyst pattern in hospitalized adult patients in our hospital from 2000 to 2010. In this study 89 patients, 50 females and 39 males who were diagnosed to have hydatid cyst were evaluated. The mean age of the patients was 37.3 and the mean hospital stay was 10.1 days. The main complaint was abdominal pain (66.2%). The most common localization of cysts was the liver and the most radiological method to diagnose the disease was ultrasonography followed by CT scan. Our recurrence rate was more than average. We had no mortality and did not find any serious postoperative complication. Safe surgery is a role for hydatid cysts.

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Section: Discussionmentioning

confidence: 96%

A retrospective survey of human hydatidosis based on hospital records during the period of 10 years

et al. 2012

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“…To increase its efficacy, albendazole must be taken daily for 4 to 6 weeks and should be repeated two or three times more. Additionally, using albendazole before and after operation was found to decrease the viability of cysts at the time of surgery, as well as significantly reducing the chances of cyst recurrence (Arif et al, 2008).…”

Section: Treatment Of Echinococcosis In Dogs With Reference To Human mentioning

confidence: 99%

Incidence and the history of Echinococcus granulosus infection in dogs within the past few decades in Libya: A review

Mohamed¹,

Wafa²,

Kawther³

et al. 2017

J. Vet. Med. Anim. Health

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Echinococcus granulosus is a tiny tapeworm that parasitizes the small intestine of canids, mainly dogs, which act as definitive hosts for the parasite. Infected dogs are the main source of infection to humans and livestock which act as intermediate hosts resulting in hydatid disease condition. E. granulosus is widely distributed in many parts of the world, and is very common in North African countries. In Libya, the rate of infection with echinococcosis in dogs was reported to be lower than 7 to 80% in stray dogs, 34.8 to 60% in sheep/guard dogs and 7.7 to 21.6% in farm/house dogs. This data fulfills the world health organization (WHO) criteria and suggests that the incidence of infection with echinococcosis/ hydatidosis in some parts of the country can be reaching the level of hyper endemic. Diagnosis of echinococcosis in infected dogs can be performed by isolating the parasite from their faeces or from the contents of their small intestine after necropsy. Recent developments in immunodiagnostic assays for echinococcosis in dogs have been described. Public health and risk factors as well as ways of hydatid disease treatment and various control strategies, including the use of veterinary vaccines, have also been discussed.

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“…11,12 US has the best diagnostic efficiency, while CT helps in the accurate anatomic localization of cysts. 13 There used to be several US classifications for liver hydatid disease, but the World Health Organization-Informal Working Group on Echinococcosis (WHO-IWGE) standardized the classification system in 2001 (Table 1). 4 Hydatid disease should be treated once it is diagnosed because the cysts usually grow and cause complications, although they can rarely collapse spontaneously and might disappear or calcify.…”

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confidence: 99%

Open Surgery for Hepatic Hydatid Disease

Sözüer

Akyüz

Akbulut

2014

International Surgery

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TurkeyHydatid disease is a zoonosis caused by the larvae of Echinococcus granulosus. Humans are an intermediate host and are usually infected by direct contact with dogs or indirectly by contaminated foods. Hydatid disease mainly involves the liver and lungs. The disease can be asymptomatic. Imaging techniques such as ultrasonography and computed tomography are used for diagnosis. The growth of hydatid cysts can lead to complications. Communication between bile duct and cysts is a common complication. The goal of treatment for hydatid disease is to eliminate the parasite with minimum morbidity and mortality. There are 3 treatment options: surgery, chemotherapy, and interventional procedures. Medical treatment has low cure and high recurrence rates. Percutaneous treatment can be performed in select cases. There are many surgical approaches for managing hydatid cysts, although there is no best surgical technique, and conservative and radical procedures are used. Conservative procedures are usually preferred in endemic areas and are easy to perform but are associated with high morbidity and recurrence rates. In these procedures, the parasite is sterilized using a scolicidal agent, and the cyst is evacuated. Radical procedures include hepatic resections and pericystectomy, which have high intraoperative risk and low recurrence rates. Radical procedures should be performed in hepatobiliary centers. The most common postoperative complications are biliary fistulas and cavityrelated complications. Endoscopic retrograde cholangiopancreatography can be used to diagnose and treat biliary system complications. Endoscopic sphincterotomy, biliary stenting, and nasobiliary tube drainage are effective for treating postoperative biliary fistulas.

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Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver

Abstract: We conclude that albendazole is safe and effective adjuvant therapy in the treatment of hydatid liver disease.

Cited by 135 publications

References 13 publications

A retrospective survey of human hydatidosis based on hospital records during the period of 10 years

A retrospective survey of human hydatidosis based on hospital records during the period of 10 years

Incidence and the history of Echinococcus granulosus infection in dogs within the past few decades in Libya: A review

Open Surgery for Hepatic Hydatid Disease

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