Akzidentelle Maculaverletzungen durch Neodym: YAG-Laser

Meyer-Riemann, W; Petersen, Jørgen Holm; Vögel, Martin

doi:10.1055/s-2008-1035108

Cited by 2 publications

(1 citation statement)

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“…Comparative biometric data from cynomolgus monkey, rhesus monkey and human subjects is listed in The damage mechanism for retinal laser exposures in the 10-ns exposure regime is believed to be primarily photomechanical in nature. [8][9][10][11] Damage occurs as a result of the rapid deposition and conversion of laser energy at high peak irradiance levels (typically near the beam focus) into thermally-induced pressure gradients. These rapidly increasing pressure gradients result in the propagation of acoustic, or shock waves in the biological media.…”

Section: Introductionmentioning

confidence: 99%

Visible lesion laser thresholds in Cynomolgus (Macaca fascicularis) retina with a 1064 nm 12-ns pulsed laser

et al. 2007

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A series of experiments in a new animal model for retinal damage, cynomolgus monkeys (Macaca fascicularis), have been conducted to determine the damage threshold for 12.5-nanosecond laser exposures at 1064 nm. These results provide a direct comparison to threshold values obtained in rhesus monkey (Macaca mulatta), which is the model historically used in establishing retinal maximum permissible exposure (MPE) limits. In this study, the irradiance level of a collimated Gaussian laser beam of 2.5 mm diameter at the cornea was randomly varied to produce a rectangular grid of exposures on the retina. Exposures sites were fundoscopically evaluated at post-irradiance intervals of 1 hour and 24 hours. Probit analysis was performed on dose-response data to obtain probability of response curves. The 50% probability of damage (ED50) values for 1 and 24 hours post-exposure are 28.5(22.7-38.4) LJ and 17.0(12.9-21.8) PU, respectively. These values compare favorably to data obtained with the rhesus model, 28.7(22.3-39.3) lJ and 19.1(13.6-24.4) pJ, suggesting that the cynomolgus monkey may be a suitable replacement for rhesus monkey in photoacoustic minimum visible lesion threshold studies.

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Section: Introductionmentioning

confidence: 99%

Visible lesion laser thresholds in Cynomolgus (Macaca fascicularis) retina with a 1064 nm 12-ns pulsed laser

et al. 2007

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A Traumatic Macular Hole Secondary to a High-Energy Nd:YAG Laser

Chuang

Lai²,

Yang³

et al. 2001

Ophthalmic Surg Lasers Imaging

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Abstract. A case is reported of a traumatic macular hole caused by a high-energy Nd:YAG laser. The initial ocular examination revealed an explosive, cratershaped, full-thickness macular hole surrounded by local edema and detachment. By the 12th day after the injury, the hole had shrunk progressively and was covered by a thin fibrin-like membrane. A thick epiretinal membrane covered the injured area 1 month after the injury. Nine months after the injury, the macular hole closed spontaneously with a partially detached epiretinal membrane. This case demonstrates one of the natural healing processes of a traumatic macular hole. Although the hole finally closed, the patient did not regain his vision because of the severe damage to the photoreceptors, retinal pigment epithelium, and choroid. [Ophthalmic Surg Lasers 2001;32:73-76]

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Akzidentelle Maculaverletzungen durch Neodym: YAG-Laser

Cited by 2 publications

References 0 publications

Visible lesion laser thresholds in Cynomolgus (Macaca fascicularis) retina with a 1064 nm 12-ns pulsed laser

Visible lesion laser thresholds in Cynomolgus (Macaca fascicularis) retina with a 1064 nm 12-ns pulsed laser

A Traumatic Macular Hole Secondary to a High-Energy Nd:YAG Laser

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