AKTIVITAS DIURESIS Leucaena leucocephala.L PADA MENCIT JANTAN (Mus musculus)

Abstract

Diuretics are compounds or drugs that can increase urine volume. This study focused on exploring the activity and concentration of ethanol extract of lamtoro leaves (Leucaenaleucocephala L.) as a diuretic in male house mice (Musmusculus) using experimental research. The method used was to observe the physical activity of urine produced for 120 minutes. Lamtoro leaves extraction was done by maceration using solvent ethanol, then phytochemical screening tests. The screening results stated positively contained alkaloids, flavonoids, terpenoids, and tannins. The animals used were 25 house mice, divided into 5 groups. Group 1 was given Na-CMC 1% w/v suspension, group 2 with furosemide suspension 0.0041% w/v, group 3 with 25% w/v lamtoro leaf ethanol extract, group 4, ethanol extract 50% w/l lamtoro leaf , and group 5 was ethanol extract 75% w/v of lamtoro leaves. Urine volume of the house mice was measured at 15, 30, 45, 60, 75, 90, 105, and 120 minutes.

Uji aktivitas diuretik ekstrak etanol daun sirih merah (Piper crocatum Ruiz & Pav) terhadap tikus putih jantan (Rattus novergicus)

“…Urin yang akan diukur volumenya diambil mengunakan spuid 1 mL. Penentuan efek diuretik dilakukan berdasarkan hasil pengukuran volume urin (Ricky Ramadhian & Pahmi, 2021).…”

Uji Invitro Aktivitas Mukolitik Ekstrak Etanol 70% Daun Lamtoro (Leucaena leucocephala (Lam) de Wit)

“…Pada tabung reaksi berisi 1 ml ekstrak etanol 70% daun lamtoro (Leucaena leucocephala (Lam) de Wit) ditambahkan FeCl3. Perubahan warna larutan menjadi hitam kebiruan atau hijau mengindikasikan kandungan senyawa tanin [10].…”

“…Mukus yang terkumpul dihomogenkan menggunakan pengaduk dengan kecepatan pelan. Mukus yang digunakan untuk pengujian mukolitik harus dalam keadaan segar [10].…”